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Title: Immunofluorescent characterization of BLBP expression during radial glial extension in the embryonic mouse (Advisor: Dr. Eva Anton - Sponsor: Dr. Steve Matson - Mentor: Dr. Ralf Schmid)
Genevieve Yancey Neuronal cells, behind intellect and memory, don’t replicate—which means that when they’re killed off by disease, toxin, or age, they’re gone forever. Yet research in brain development may provide physicians with the tools to stimulate new growth and reverse this degeneration. In the embryonic stages of development, cells known as radial glia provide an infrastructure to direct neuronal migration. My research concerns BLBP, a protein expressed by these glial cells, which plays a role in the movement of their “finger-like” extensions. By using techniques like immunofluorescent staining, we can better characterize the specific regions and time of BLBP activity, thus getting at its precise function in the glial extension process. |
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