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Title: Isopeptide Bonds, Formed by Transglutaminase Enzymes, Accumulate in Articular Cartilage During Development and May Give Cartilage Mechanical Strength (Advisor: Dr. Greta Lee - Sponsor: Dr. Walter Bollenbacher - Mentor: Dr. Ron Graph)
Shirin Peters I am trying to show there is a correlation between the enzyme tTG, found in articular cartilage, and the mechanical strength of cartilage. For this purpose, I am observing changes in the expression of tTG by comparing the concentration of isopeptide bonds, known to be formed by tTG, in neo-cartilage samples in different stages of development (as mechanical strength increases during development.) |
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