Recent Publications by Graduate Students in Biology Labs
(only selected papers on which a graduate student is first or co-first author are listed)

2008

J.L. Knies, K.K. Dang, T.J. Vision, N.G. Hoffman, R. Swanstrom and C.L. Burch (2008) Compensatory evolution in RNA secondary structures increases substitution rate variation among sites. Mol Biol Evol 25: 1778-1787

N.C. Kappas, G. Zeng, J.C. Chappell, J.B. Kearney, S. Hazarika, K.G. Kallianos, C. Patterson, B.H. Annex and V.L. Bautch (2008) The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. J Cell Biol 181: 847-858

K.S. Christine and F.L. Conlon (2008) Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midline. Devel cell 14: 616-623

J.D. Merker, M. Dominska, P.W. Greenwell, E. Rinella, D.C. Bouck, Y. Shibata, B.D. Strahl, P. Mieczkowski and T.D. Petes (2008) The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. DNA Repair 7: 1298-1308

M.M. Koseoglu, L.M. Graves and W.F. Marzluff (2008) Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase. Mol Cell Biol 28: 4469-4479

T.K. Eitas, Z.L. Nimchuk and J.L. Dangl (2008) Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB. Proc Natl Acad Sci 105: 6475-6480

A.M. Rice and D.W. Pfennig (2008) Analysis of range expansion in two species undergoing character displacement: why might invaders generally 'win' during character displacement? J Evol Biol 21: 696-704

G.R. Harper, Jr. and D.W. Pfennig (2008) Selection overrides gene flow to break down maladaptive mimicry. Nature 451: 1103-1106

J.P. To and J.J. Kieber (2008) Cytokinin signaling: two-components and more. Trends Plant Sci 13: 85-92

C.C. Homem and M. Peifer (2008) Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis. Development 135: 1005-1018

N. Ko, R. Nishihama and J.R. Pringle (2008) Control of 5-FOA and 5-FU resistance by Saccharomyces cerevisiae YJL055W. Yeast 25: 155-160

N.G. Cakmakci, R.S. Lerner, E.J. Wagner, L. Zheng and W.F. Marzluff (2008) SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein. Mol Cell Biol 28: 1182-1194

L. E. Berchowitz and G. P. Copenhaver (2008) Division of Labor Among Meiotic Genes. Nature Genetics 40: 266-267.

L. E. Berchowitz and G. P. Copenhaver (2008) Fluorescent Arabidopsis tetrads: A visual assay for quickly developing large crossover and crossover interference datasets. Nature Protocols 3(1): 41-50.

2007

K. E. Francis, S. Y. Lam, B. D. Harrison, A. L. Bey, L. E. Berchowitz and G. P. Copenhaver (2007) Pollen Tetrad-based Visual Assay for Meiotic Recombination in Arabidopsis. Proc. Natl. Acad. Sci. 104: 3913-3918.

W. N. Gabriel, R. McNuff, S.K. Patel, T.R. Gregory, W.R. Jeck, C.D. Jones and B. Goldstein (2007) The Tardigrade Hypsibius dujardini, a New Model for Studying the Evolution of Development. Developmental Biology 312: 545-559. (Faculty of 1000 Must Read)

L.E. Berchowitz, K.E. Francis, A.L. Bey, and G.P. Copenhaver (2007) The role of AtMUS81 in interference-insensitive crossovers in A. thaliana. PLoS Genet 3: e132.

D.C. Bouck and K. Bloom (2007) Pericentric chromatin is an elastic component of the mitotic spindle. Curr Biol 17: 741-748.

D.D. Brown, K. Christine, C. Showell, and F.L. Conlon (2007) The heat shock protein HSP-27 is required for cardiac midline fusion. Genesis 3: 667-678.

D.T. Fox and M. Peifer (2007) Cell adhesion: separation of p120's powers? Curr Biol 17: R24-27.

D.T. Fox and M. Peifer (2007) Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila. Development 134: 567-578.

W.N. Gabriel and B. Goldstein (2007) Segmental expression of Pax3/7 and Engrailed homologs in tardigrade development. Devel Genes Evol 312: 545-559. (Faculty of 1000 Must Read)

S.C. Goetz and D.L. Conlon (2007) Control of embryonic cardiac cell cycle. Cell Cycle 6: 1974-1981.

M.A. Hayden, K. Akong and M. Peifer (2007) Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev Biol 305: 358-376.

Y.G. Langdon, S.C. Goetz, A.E. Berg, J.T. Swanik, and F.L. Conlon (2007) SHP-2 is Required for the Maintenance of Cardiac Progenitors. Development 134: 4119-4130.

J.R. LaRocque, B. Jaklevic, T.T. Su, and J. Sekelsky (2007) Drosophila ATR in double-strand break repair. Genetics 175: 1011–1022.

J.R. LaRocque, D. Dougherty, S. Hussain, and J. Sekelsky (2007) Reducing DNA polymerase α in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects. Genetics (in press).

Z.L. Nimchuk, E.J. Fisher, D. Desveaux, J.H. Chang and J.L. Dangl (2007) The HopX (AvrPphE) family of Pseudomonas syringae type III effectors require a catalytic triad and a novel N-terminal domain for function. Mol. Plant Microb Interact 20: 346-357

S.J. Radford, M. Sabourin, S. McMahan, and J. Sekelsky (2007) Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts. Genetics 176: 53–62.

S.J. Radford, S. McMahan, H.L. Blanton, and J. Sekelsky (2007) Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants. Genetics 176: 63–72.

S. Shibutani, L.M. Swanhart and R.J. Duronio (2007) Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis. Development 134: 467-478.

L.M. Swanhart, A.N. Sanders, and R.J. Duronio (2007) Normal regulation of Rbf1/E2f1 target genes in Drosophila type I protein phosphatase mutants. Developmental Dynamics 236: 2567-2577.

K. Trowbridge, K.S. McKim, S.J. Brill, and J. Sekelsky (2007) Synthetic lethality in the absence of the Drosophila MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis. Genetics (in press).

T.A. Uyeno and W.M. Kier (2007) Electromyography of the buccal musculature of octopus (Octopus bimaculoides): a test of the function of the muscle articulation in support and movement. J. Exper Biol 210: 118-128.

E.J. Wagner, B.D Burch, A.C. Godfrey, H.R. Salzler, R.J. Duronio, and W.F. Marzluff (2007) A Genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing. Mol. Cell 30:692-699.

A.E. White, M.E. Leslie, B.R. Calvi, W.F. Marzluff, and R.J. Duronio (2007) Developmental and cell cycle regulation of the Drosophila histone locus body.. Mol Biol Cell 18: 2491-2502.

2006

A. B. Robertson, S. R. Pattishall, E. Gibbons and S. W. Matson (2006) MutL-catalyzed ATP hydrolysis is required at a post-UvrD loading step in methyl-directed mismatch repair. coli. J. Biol. Chem 281: 19949-19959.

A. B. Robertson, S. R. Pattishall and S. W. Matson (2006) The DNA binding activity of MutL is required for methyl-directed mismatch repair in E. coli. J. Biol. Chem 281: 8399-8408.

D.D. Brown, A.C. Davis, and F.L. and Conlon (2006) Xtn3 is a developmentally expressed cardiac and skeletal muscle-specific novex-3 titin isoform. Gene Expression Patterns 6: 913-918.

S. Duffy, P.E. Turner, and C.L. Burch (2006) Pleiotropic costs of niche expansion in the RNA bacteriophage phi-6. Genetics 172: 751-757.

A.C. Godfrey, J.M. Kupsco, B.D. Burch, R.M. Zimmerman, Z. Dominski, W.F. Marzluff, and R.J. Duronio (2006) U7 snRNA mutations in Drosophila block histone pre-mRNA processing and disrupt oogenesis. RNA 12: 396-409.

S.C. Goetz, D.D. Brown, and F.L. Conlon (2006) TBX5 controls cardiac cell cycle progression. Development 133: 2575-84.

J.L. Knies, R. Izem, K.L. Supler, J.G. Kingsolver, and C.L. Burch (2006) The genetic basis of thermal reaction norm evolution in lab and natural phage populations. PLoS Biology 4: e201.

J.M. Kupsco, M.J. Wu, W.F. Marzluff, R. Thapar, and R.J. Duronio (2006). Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases. RNA 12: 2103-2117.

J.Y. Lee, D.J. Marston, T. Walston, J. Hardin, A. Halberstadt, and B. Goldstein (2006) Wnt/Frizzled signaling controls C. elegans gastrulation by activating actomyosin contractility. Curr Biol 16: 1986-1997.      Faculty of 1000 Must Read     Curr Biol Dispatch

M.W. Lewis, M.E. Leslie and S.J. Liljegren (2006) Plant separation: 50 ways to leave your mother. Curr Opin Plant Biol 9: 59-65

E.K. McCarthy and B. Goldstein (2006) Asymmetric spindle positioning. Curr Opin Cell Biology 18: 79-85.

J.N. Molk, E.D. Salmon, and K. Bloom (2006) Nuclear congression is driven by cytoplasmic microtubule plus end interactions in S. cerevisiae. J Cell Biol 172: 27-39.

J.N. Molk and K. Bloom (2006) Microtubule dynamics in the budding yeast mating pathway. J Cell Sci 119: 3485-3490.

C.G. Pearson, M.K. Gardner, L.V. Paliulis, E.D. Salmon, D.J. Odde, and K. Bloom (2006) Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy. Mol Biol Cell (in press).

A. Robertson, S.R. Pattishall, and S.W. Matson (2006) The DNA binding activity of MutL is required for methyl-directed mismatch repair in Escherichia coli. J Biol Chem 281: 8399-408.

A. Robertson, S.R. Pattishall, E.A. Gibbons, and S.W. Matson (2006) MutL-catalyzed ATP hydrolysis is required at a post-UvrD loading step in methyl-directed mismatch repair. J Biol Chem 281: 19949-59.

J.R.A. Taylor and W.M. Kier (2006) A pneumo-hydrostatic skeleton in land crabs. Nature 440: 1005.

2005

D. S. Monroe Jr., A. K. Leitzel, H. L. Klein and S. W. Matson (2005) Biochemical and genetic characterization of hmi1p, a yeast DNA helicase involved in the maintenance of mitochondrial DNA. Yeast 22: 1269-1286.

S. Y. Lam, S. J. Radford, E. A. Housworth, F. W. Stahl and G. P. Copenhaver (2005) Crossover interference on the NOR bearing chromosomes or Arabidopsis. Genetics 170: 807-812.

H.L. Blanton, S.J. Radford, S. McMahan, H.M. Kearney, J.G. Ibrahim and J. Sekelsky (2005) REC, Drosophila MCM8, drives formation of meiotic crossovers. PLoS Genetics 1: 343-354.
     Faculty of 1000 Must Read

D.C. Bouck and K.S. Bloom (2005) The kinetochore protein Ndc10p is required for spindle stability and cytokinesis in yeast. Proc Natl Acad Sci 102: 5408-5413.

D.D. Brown, S.N. Martz, O. Binder, S.C. Goetz, B.M. Price, J.C. Smith and F.L. Conlon (2005) Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis. Development 132: 553-563.
     Faculty of 1000 Recommended

N.R. Dudley, A.Z. Amin and B. Goldstein (2005) Genes Required for RNA Interference, pp 55-68 in RNA Interference Technology: From Basic Science to Drug Development, edited by K. Appasani (Cambridge University Press).

N.R. Dudley and B. Goldstein (2005) RNA Interference in Caenorhabditis elegans. Chapter in RNA Silencing: Methods and Protocols. Ed. by G. Carmichael. Methods in Molecular Biology 309: 29-38  (Humana Press).

J.A. Erkmann, R. Sanchez, N. Treichel, W.F. Marzluff and U. Kutay (2005) Nuclear export of metazoan replication-dependent histone mRNAs is dependent on RNA length and is mediated by TAP. RNA 11: 45-58.

J.A. Erkmann, E.J. Wagner, J. Dong, Y. Zhang, U. Kutay and W.F. Marzluff (2005) Nuclear import of the stem-loop binding protein and localization during the cell cycle. Mol Biol Cell 16: 2960-2971.

D.T. Fox, C.C.F. Homem, S.H. Myster, F. Wang, E.E. Bain and M. Peifer (2005) Rho1 regulates Drosophila adherens junctions independently of p120ctn. Development 132: 4819-31.

W.P. Irwin and K.J. Lohmann (2005) Disruption of magnetic orientation in hatchling loggerhead sea turtles by pulsed magnetic fields. J Comp Physiol 191: 475-480.

H. Kaygun and W.F. Marzluff (2005) Translation termination is involved in histone mRNA degradation when DNA replication is inhibited. Mol Cell Biol 25: 6879-6888.

H. Kaygun and W.F. Marzluff (2005) Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1. Nat Struct Mol Biol 12: 794-800.

E.M. Mandel, T.E. Callis, D.Z. Wang, and F.L. Conlon, (2005) Transcriptional mechanisms of congenital heart disease. Drug Discovery Today: Disease Mechanisms 2: 33-38.

E.K. McCarthy and B. Goldstein (2005) Asymmetric division: A kinesin for spindle positioning. Current Biology 15: R591-593.

D.S. Monroe, A.K. Leitzel, H.L. Klein, and S.W. Matson (2005) Biochemical and genetic characterization of Hmi1p, a yeast DNA helicase involved in the maintenance of mitochondrial DNA. Yeast 22: 1269-1286

S.J. Radford, E. Goley, K. Baxter, S. McMahan and J. Sekelsky (2005) Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers. Genetics 170: 1737-1745.

B. Rao, Y. Shibata, B.D. Strahl and J.D. Lieb (2005) Dimethylation of histone H3 at lysine 36 demarcates regulatory and non-regulatory chromatin genome-wide. Mol Cell Biol 25: 9447-9459.

L. Swanhart, J. Kupsco and R.J. Duronio (2005) Developmental control of growth and cell cycle progression in Drosophila. Methods Mol Biol 296: 69-94.

2004

L. Avens and K.J. Lohmann (2004) Navigation and seasonal migratory orientation in juvenile sea turtles. J Exp Biol 207: 1771-1778.

R.J. Cheeks, J.C. Canman, W.N. Gabriel, N. Meyer, S. Strome and B. Goldstein (2004) C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes. Current Biol 14: 851-862.

T.D. Donaldson, M.A. Noureddine, P.J. Reynolds, W. Bradford, R.J. Duronio (2004) Targeted Disruption of Drosophilla Roc1b Reveals Functional Differences in the Roc Subunit of Cullin-dependent E3 Ubiquitin Ligases. Mol Biol of the Cell 15: 4892-4903

K.A. Hogan, C.A. Ambler, D.L. Chapman and V.L. Bautch (2004) The neural tube patterns vessels developmentally using the VEGF signaling pathway. Development 131: 1503-1513.

J.B. Kearney, N.C. Kappas, C. Ellerstrom, F.W. DiPaola and V.L. Bautch (2004) The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis. Blood 103: 4527-4535.

Y.-S. Kuan, P. Brewer-Jensen and L.L. Searles (2004)Suppressor of (sable), a putative RNA processing protein, functions at the level of transcription. Mol Cell Biol 24: 3734-3746.

D.J. Lanzotti, J.M. Kupsco, X.-C. Yang, Z. Dominski, W.F. Marzluff and R.J. Duronio (2004)Drosophila SLBP intracellular localization is mediated by phosphorylation and is required for cell cycle-regulated histone mRNA expression. Mol Cell Biol 15: 1112-1123.

T. Li, C.-Y. Chang, D.-Y. Jin, P.-J. Lin, A. Khvorova and D.W. Stafford (2004) Identification of the gene for vitamin K epoxide reductase. Nature 427: 541-544.

M. McVey, J.R. LaRocque, M.D. Adams and J. Sekelsky (2004) Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion. Proc Natl Acad Sci 101: 15694-15699.
     Faculty of 1000 Recommended

J.N. Molk, S.C. Schuyler, J.Y. Liu, J.G. Evans, E.D. Salmon, D. Pellman and K. Bloom (2004) The Differential Roles of Budding Yeast Tem1p, Cdc15p, and Bub2p Protein Dynamics in Mitotic Exit. Mol Biol Cell 15: 1519-1532.

K. Mythreye and K.S. Bloom (2004)Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J Cell Biol 160:833-43.

D.M. Roberts, A.L. Anderson, M. Hidaka, R.L. Swetenburg, C. Patterson, W.L. Stanford and V.L. Bautch (2004) A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Mol Cell Biol 24: 10515-10528.

D. Roberts, J.B. Kearney, J.H. Johnson, M.P. Rosenberg, R. Kumar and V.L. Bautch (2004) The VEGF receptor flt-1 (VEGFR-1) modulates flk-1 (VEGFR-2) signaling during blood vessel formation.American Journal of Pathology 164: 1531-1535.

R. Sanchez and W.F. Marzluff (2004)The oligoA tail on histone mRNA plays an active role in translational silencing of histone mRNA during Xenopus oogenesis.Mol Cell Biol 24: 2513-2525.

J.P.C. To, G. Haberer, F.J. Ferreira, J. Deručre, M.G. Mason, G.E. Schaller, J.M. Alonso, J.R. Ecker and J.J. Kieber (2004)Type-A ARRs are partially redundant negative regulators of cytokinin signaling in Arabidopsis. Plant Cell 16: 658-671.

J.H. Wang, S.D. Cain and K.J. Lohmann (2004) Identifiable neurons inhibited by Earth-strength magnetic stimuli in the mollusc Tritonia diomedea. J Exp Biol 207: 1043-1049.

M.L. Whitfield, H. Kaygun, J.A. Erkmann, W.H. Townley-Tilson, Z. Dominski and W.F. Marzluff (2004) SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP. Nucleic Acids Res 32: 4833-4842.

O. Yildiz, H.M. Kearney, B. Kramer and J.J. Sekelsky (2004)Mutational analysis of the Drosophila DNA repair and recombination gene mei-9. Genetics 167: 263-273.

2003

C.A. Ambler, G.M. Schmunk and V.L. Bautch (2003) Stem cell-derived endothelial cells/progenitors migrate and pattern in the embryo using the VEGF signaling pathway. Dev Biol 257: 205-219.

V. Anest, J.L. Hanson, P.C. Cogswell, K.A. Steinbrecher, B.D. Strahl and A.S. Baldwin (2003) A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature 423: 659-663.

L. Avens and K.J. Lohmann (2003) Use of multiple orientation cues by juvenile loggerhead sea turtles Caretta caretta. J Exp Biol 206: 4317-4325.

L.C. Boles and K.J. Lohmann (2003) True navigation and magnetic maps in spiny lobsters. Nature 421: 60-63.

D.D. Brown, O. Binder, M. Pagratis, B.A. Parr and F.L. Conlon (2003) Developmental expression of the Xenopus laevis Tbx20 orthologue. Dev Genes Evol 212: 604-607.

J.C. Canman, L.A. Cameron, P.S. Maddox, A. Straight, J.S. Tirnauer, T.J. Mitchison, G. Fang, T.M. Kapoor and E.D. Salmon (2003) Determining the position of the cell division plane. Nature 424: 1074-1078.

P. Cayirlioglu, W.O. Ward, S.C. Silver Key and R.J. Duronio (2003) Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. Mol Cell Biol 23: 2123-2134.

N.R. Dudley and B. Goldstein (2003). RNA interference: Silencing in the cytoplasm and nucleus. Curr Opin Mol Ther 5: 113-117.

E.E. Grevengoed, D.T. Fox, J. Gates and M. Peifer (2003) Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled. J Cell Biol 163: 1267-1279.

A.T. Groover, A. Pattishall and A.M. Jones(2003) AA8 expression during vascular cell differentiation. Plant Mol Biol 51: 427-435.

B.F. Holt, 3rd, D.A. Hubert and J.L. Dangl (2003) Resistance gene signaling in plants--complex similarities to animal innate immunity. Curr Opin Immunol 15: 20-25.

D.A. Hubert, P. Tornero, Y. Belkhadir, P. Krishna, A. Takahashi, K. Shirasu and J.L. Dangl (2003) Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 disease resistance protein. EMBO J 22: 5679-5689.

W.P. Irwin and K.J. Lohmann (2003) Magnet-induced disorientation in hatchling loggerhead sea turtles. J Exp Biol 206: 497-501.

J.B. Kearney and V.L. Bautch (2003) In vitro differentiation of mouse ES cells: hematopoietic and vascular development. Methods Enzymol 365: 83-98.

J.Y. Lee and B. Goldstein (2003) Mechanisms of cell positioning during C. elegans gastrulation. Development 130: 307-320.
     A Preview article about this paper was published in Developmental Cell 4: 6-8 (2003).
     A Dispatch article about this paper and one other was published in Current Biology 13: R223-5 (2003).
     Faculty of 1000 Must Read

P.S. Maddox, B. Moree, J.C. Canman and E.D. Salmon (2003) Spinning disk confocal microscope system for rapid high-resolution, multimode, fluorescence speckle microscopy and green fluorescent protein imaging in living cells. Methods Enzymol 360: 597-617.

P. Maddox, A. Straight, P. Coughlin, T.J. Mitchison and E.D. Salmon (2003) Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. J Cell Biol 162: 377-382.

P.S. Maddox, J.K. Stemple, L. Satterwhite, E.D. Salmon and K. Bloom (2003) The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast. Curr Biol 13: 1423-1428.

J.C. Mallory, V.I. Bashkirov, K.M. Trujillo, J.A. Solinger, M. Dominska, P. Sung, W.D. Heyer and T.D. Petes (2003) Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. DNA Repair (Amst) 2: 1041-1064.

J.D. Merker, M. Dominska and T.D. Petes (2003) Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 165: 47-63.

K. Mythreye and K.S. Bloom (2003) Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J Cell Biol 160: 833-843.

Z. Nimchuk, T. Eulgem, B.F. Holt, 3rd and J.L. Dangl (2003) Recognition and response in the plant immune system. Annu Rev Genet 37: 579-609.

A.Z. Ozsoy, H.M. Ragonese and S.W. Matson (2003) Analysis of helicase activity and substrate specificity of Drosophila RECQ5. Nucleic Acids Res 31: 1554-1564.

C.G. Pearson, P.S. Maddox, T.R. Zarzar, E.D. Salmon and K. Bloom (2003) Yeast kinetochores do not stabilize Stu2p-dependent spindle microtubule dynamics. Mol Biol Cell 14: 4181-4195.

J.R. Taylor and W.M. Kier (2003) Switching skeletons: hydrostatic support in molting crabs. Science 301: 209-210.

Q. Tian, P. Nagpal and J.W. Reed (2003) Regulation of Arabidopsis SHY2/IAA3 protein turnover. Plant J 36: 643-651.

H. Ullah, J.G. Chen, B. Temple, D.C. Boyes, J.M. Alonso, K.R. Davis, J.R. Ecker and A.M. Jones (2003) The beta-subunit of the Arabidopsis G protein negatively regulates auxin-induced cell division and affects multiple developmental processes. Plant Cell 15: 393-409.

J.H. Wang, S.D. Cain and K.J. Lohmann (2003) Identification of magnetically responsive neurons in the marine mollusc Tritonia diomedea. J Exp Biol 206: 381-388.

2002

K. Akong, E.E. Grevengoed, M.H. Price, B.M. McCartney, M.A. Hayden, J.C. DeNofrio and M. Peifer. (2002).Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev Biol 250: 91-100.

K. Akong, B.M. McCartney and M. Peifer. (2002). Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev Biol 250: 71-90.

D.R. Byrd, J.K. Sampson, H.M. Ragonese and S.W. Matson (2002) Structure-function analysis of Escherichia coli DNA helicase I reveals non-overlapping transesterase and helicase domains. J Biol Chem 277: 42645-42653.

D.H. Aviv, C. Rusterucci, B.F. Iii, R.A. Dietrich, J.E. Parker and J.L. Dangl. (2002). Runaway cell death, but not basal disease resistance, in lsd1 is SA- and NIM1/NPR1-dependent. Plant J 29: 381-391.

J.C. Canman, N. Sharma, A. Straight, K.B. Shannon, G. Fang and E.D. Salmon. (2002). Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins. J Cell Sci 115: 3787-3795.

J.C. Canman, E.D. Salmon and G. Fang. (2002). Inducing precocious anaphase in cultured mammalian cells. Cell Motil Cytoskeleton 52: 61-65.

N.R. Dudley, J.C. Labbe and B. Goldstein. (2002). Using RNA interference to identify genes required for RNA interference. Proc Natl Acad Sci USA 99: 4191-4196.
      A New & Notable abstract about this paper was published in The Scientist (2002) 16[10]:41.
      A Research News article about this paper was published in Genome Biology (2002)  March.
      An interview about this work was published in RNAi News, Feb 2004.
      Faculty of 1000 Must Read

B.F. Holt, 3rd, D.C. Boyes, M. Ellerstrom, N. Siefers, A. Wiig, S. Kauffman, M.R. Grant and J.L. Dangl. (2002). An evolutionarily conserved mediator of plant disease resistance gene function is required for normal Arabidopsis development. Dev Cell 2: 807-817.

J.B. Kearney, C.A. Ambler, K.A. Monaco, N. Johnson, R.G. Rapoport and V.L. Bautch. (2002). Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99: 2397-407.

D.J. Lanzotti, H. Kaygun, X. Yang, R.J. Duronio and W.F. Marzluff. (2002). Developmental control of histone mRNA and dSLBP synthesis during Drosophila embryogenesis and the role of dSLBP in histone mRNA 3' end processing in vivo. Mol Cell Biol 22: 2267-2282.

K. Maleck, U. Neuenschwander, R.M. Cade, R.A. Dietrich, J.L. Dangl and J.A. Ryals (2002) Isolation and characterization of broad-spectrum disease-resistant Arabidopsis mutants. Genetics 160: 1661-1671.

M.A. Noureddine, T.D. Donaldson, S.A. Thacker and R.J. Duronio. (2002). Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase. Dev Cell 2: 757-770.

H.P. Shih, K.G. Hales, J.R. Pringle and M. Peifer. (2002). Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila. J Cell Sci 115: 1259-1271.

Q. Tian, N.J. Uhlir and J.W. Reed. (2002). Arabidopsis SHY2/IAA3 inhibits auxin-regulated gene expression. Plant Cell 14: 301-319.

O. Yildiz, S. Majumder, B. Kramer and J. Sekelsky. (2002). Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers. Molecular Cell 10: 1503-1509.

2001

C.A. Ambler, J.L. Nowicki, A.C. Burke and V.L. Bautch. (2001). Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts. Dev Biol 234: 352-364.

D.L. Beach and K. Bloom. (2001). ASH1 mRNA localization in three acts. Mol Biol Cell 12: 2567-2577.

P. Cayirlioglu, P.C. Bonnette, M.R. Dickson and R.J. Duronio. (2001). Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development 128: 5085-5098.

P. Cayirlioglu and R.J. Duronio. (2001). Cell cycle: Flies teach an old dogma new tricks. Curr Biol 11: R178-181.

J.G. Chen, H. Ullah, J.C. Young, M.R. Sussman, and A.M. Jones. (2001) ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis. Genes Dev. 15: 902-11

E.E. Grevengoed, J.J. Loureiro, T.L. Jesse and M. Peifer. (2001). Abelson kinase regulates epithelial morphogenesis in Drosophila. J Cell Biol 155: 1185-1198.

H.M. Kearney, D.T. Kirkpatrick, J.L. Gerton and T.D. Petes. (2001). Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. Genetics 158: 1457-1476.

J.J. Loureiro, K. Akong, P. Cayirlioglu, A.E. Baltus, A. DiAntonio and M. Peifer. (2001). Activated armadillo/beta-catenin does not play a general role in cell migration and process extension in Drosophila. Dev Biol 235: 33-44.

Z. Nimchuk, L. Rohmer, J.H. Chang and J.L. Dangl. (2001). Knowing the dancer from the dance: R-gene products and their interactions with other proteins from host and pathogen. Curr Opin Plant Biol 4: 288-294.

A.Z. Ozsoy, J. Sekelsky and S.W. Matson. (2001). Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase. Nucleic Acids Res 29: 2986-9293.

C.G. Pearson, P.S. Maddox, E.D. Salmon and K. Bloom. (2001). Budding yeast chromosome structure and dynamics during mitosis. J Cell Biol 152: 1255-1266.

C. Rusterucci, D.H. Aviv, B.F. Holt, 3rd, J.L. Dangl and J.E. Parker (2001) The disease resistance signaling components EDS1 and PAD4 are essential regulators of the cell death pathway controlled by LSD1 in Arabidopsis. Plant Cell 13: 2211-2224.

E. Sullivan, C. Santiago, E.D. Parker, Z. Dominski, X. Yang, D.J. Lanzotti, T.C. Ingledue, W.F. Marzluff and R.J. Duronio. (2001). Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression. Genes Dev 15: 173-187.

Recent Awards to Graduate Students in Biology Laboratories

2008

Kathleen Christine (Conlon) was awarded an American Heart Association Predoctoral Fellowship.

2006

Daniel Brown (Conlon) and Sarah Radford (Sekelsky) won Lineberger Cancer Center Graduate Fellow awards.

Matt Fruxjager (Lohmann) was awarded a National Science Foundation Predoctoral Fellowship.

2005

Nate Dudley (Goldstein) won the Lineberger Cancer Center Graduate Fellow award.

Mia Lowden (Ahmed) was awarded a National Research Service Award Minority Predoctoral Fellowship.

2004

Joanna Fried (Bautch) is the recipient of a Kenan Graduate Fellowship.

Nick Kappas (Bautch) won the Best Poster competition at the Developmental Vascular Biology Workshop in Asilomar, CA.

Elizabeth Mandel (Conlon) was awarded a National Science Foundation Predoctoral Fellowship.

Amber Rice (D. Pfennig) was awarded a National Science Foundation Predoctoral Fellowship.

2003

Jan LaRocque (Sekelsky) was awarded a National Science Foundation Predoctoral Fellowship.

Nick Kappas (Bautch) was awarded an American Heart Association Predoctoral Fellowship.

Zachary Nimchuk(Dangl) was awarded the W.C. Coker Dissertation Fellowship, University of North Carolina at Chapel Hill.

Chad Pearson (Bloom) won the Lineberger Cancer Center Graduate Fellowship.

2002

Daniel Brown (Conlon) was awarded a National Science Foundation Predoctoral Fellowship.

Dave Roberts (Bautch) was awarded a DOD Predoctoral Fellowship.

Paul Maddox (Salmon) won the Harold Weintraub Graduate Student Award from the Fred Hutchison Cancer Research Center

2001

Joe Kearney (Bautch) was awarded the Edwards-Hopgood Graduate Student Award.

Sarah Radford (Sekelsky) was named to the Royster Society of Fellows

Özlem Yildiz (Sekelsky) was awarded a Graduate Student Mentor award from the Office of Undergraduate Research.

Recent Talks by Graduate Students at National and International Meetings

2006

Jan LaRocque (Sekelsky): "The role of Drosophila ATR in double-strand break repair" at 3^rd International Workshop on Drosophila Cell Division Cycle (Porto, Portugal) .

2005

Nate Dudley (Goldstein): "The identification of six new genes required for RNAi" at International C. elegans Conference (Los Angeles, CA).

Willow Gabriel (Goldstein): "Developing Tardigrades as a New Model for Studying the Evolution of Development" at Society for Integrative and Comparative Biology Annual Meeting (San Diego, CA).

Jen Lee (Goldstein): "Wnt/Frizzled signaling regulates actomyosin contraction during C. elegans gastrulation" at International C. elegans Conference (Los Angeles).

Don Fox (Peifer): "Abelson kinase coordinates apical constriction and RhoGEF2 localization during Drosophila morphogenesis" at the American Society for Cell Biology National Meeting (San Francisco, CA).

Patrick Reynolds (Duronio): "Preferential binding between specific Rocs and Cullins contributes to the functional differences among D. melanogaster Cullin-RING E3 Ubiquitin lLigases" at the Ubiquitin Family Meeting (Cold Spring Harbor, NY).

2004

Nate Dudley (Goldstein): "A role for nuclear proteins in RNAi in animal cells" at American Association for Cancer Research Annual Meeting (Orlando, FL).

Jan LaRocque (Sekelsky): "Drosophila Atr in DNA double-strand break repair." at Genetics Society of America Drosophila Research Conference (Washington, D.C.).

Zachary Nimchuk (Dangl): Pseudomonas syringae type III effector functions during host infection." International Joint Workshop on PR-Proteins and Induced Resistance (Helsingor, Denmark). "

2003

Lizz Grevengoed (Peifer): "Abelson kinase regulates the apical actin cytoskeleton." at Genetics Society of America Drosophila Research Conference (Chicago).

Nate Dudley (Goldstein): "Unwinding the mysteries of RNA interference: A conserved RNA helicase with double-stranded RNA binding domains is required for RNAi in C. elegans." at International C. elegans Conference (Los Angeles).

Jen Lee (Goldstein): "Mechanisms of cell positioning during C. elegans gastrulation." at American Society for Cell Biology Meeting (San Francisco).

2002

Kathryn Akong (Peifer): "Novel Functions of dAPC2 in Cytoskeletal Organization and Cell Fate." at Genetics Society of America Drosophila Research Conference (San Diego).

Hunter Blanton (Sekelsky): "Genetic and molecular characterization of recombination-defective (rec), an MCM-like gene required for meiotic recombination" at Genetics Society of America Drosophila Research Conference (San Diego).

Pelin Cayirlioglu (Duronio) "E2F2 is required for normal axis determination during oogenesis." at Genetics Society of America Drosophila Research Conference (San Diego).

Zachary Nimchuk (Dangl): 13^th International Conference on Arabidopsis Research. Seville, Spain. “TAO1, a link between resistant and susceptible host responses to the Pseudomonas syringae type III effector AvrB.

2001

Nate Dudley (Goldstein): "Using RNAi to identify new components of the RNAi machinery." at International C. elegans Conference (Los Angeles).

Lizz Grevengoed (Peifer): "Abelson kinase modulates epithelial cell adhesion, polarity and morphogenesis." at Genetics Society of America Drosophila Research Conference (Washington, D.C.).

Özlem Yildiz (Sekelsky): "The function of MEI-9 and its partners in DNA repair and recombination pathways." at Genetics Society of America Drosophila Research Conference (Washington, D.C.).