Jeff Sekelsky Publications

Sekelsky Lab Publications

D.T. Bergstralh and J. Sekelsky (2008) Interstrand crosslink repair: can XPF-ERCC1 be let off the hook? Trends Genet. (in press).

K. Trowbridge, K.S. McKim, S.J. Brill, and J. Sekelsky (2007) Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis. Genetics 176: 1993-2001.

M. McVey, S. Andersen, Y. Broze, and J. Sekelsky (2007) Multiple functions of the Drosophila Blm helicase in maintaining genome stability. Genetics 176: 1979-1992..

J. LaRocque, D.L. Dougherty, S. Hussain, and J. Sekelsky (2007) Reducing DNA polymerase &alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects. Genetics 176: 1441–1451.

S.J. Radford, M. Sabourin, S. McMahan, and J. Sekelsky (2007) Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts. Genetics 176: 52-63.

S.J. Radford, S. McMahan, H. Blanton, and J. Sekelsky (2007) Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants. Genetics 176: 63-72.

J. LaRocque, B. Jaklevic, T.T. Su, and J. Sekelsky (2007) Drosophila ATR in double-strand break repair. Genetics 175: 1023–1033.

H. Blanton, S.J. Radford, H. Kearney, S. McMahan, J. Ibrahim, and J. Sekelsky (2005) REC, Drosophila MCM8, drives formation of meiotic crossovers. PLoS Genetics 1: e40. Faculty of 1000: Must read (new finding)

S.J. Radford, E. Goley, K. Baxter, S. McMahan, and J. Sekelsky (2005) Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers. Genetics 170: 1737-1745.

M. McVey, J. LaRocque, M.D. Adams, and J. Sekelsky (2004) Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion. Proc Natl Acad Sci 101: 15694-15699. Faculty of 1000: Recommended (new finding, controversial)

H. Blanton and J. Sekelsky (2004) Unique invasions and resolutions: DNA repair proteins in meiotic recombination in Drosophila melanogaster. Cytogen Genome Res 107: 172-179.

M. McVey, D. Radut, and J. Sekelsky (2004) End-joining repair of double-strand breaks in Drosophila is largely DNA ligase IV-independent. Genetics 168: 2067-2076.

M. McVey, M.D. Adams, E. Staeva-Vieira, and J. Sekelsky (2004) Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila. Genetics 167: 699-705.

Ö. Yildiz, H. Kearney, B.C. Kramer, and J. Sekelsky (2004) Mutational analysis of the Drosophila DNA repair and recombination gene mei-9. Genetics 167: 263-273.

S.J. Radford and J. Sekelsky (2004) Taking Drosophila Rad51 for a SPiN. Nature Struct Mol Biol 11: 9-10.

M.D. Adams, M. McVey, and J. Sekelsky (2003) Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing. Science 299: 265-267. Winner of Joseph S. Pagano Award for Outstanding Publication by Postdoctoral Fellows

Ö. Yildiz, S. Majumder, B.C. Kramer, and J. Sekelsky (2002) Drosophila MUS312 protein interacts physically with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers. Molecular Cell 10: 1503-1509.

M.D. Adams and J. Sekelsky (2002) From sequence to phenotype: reverse genetics in Drosophila melanogaster. Nature Rev Genetics 3: 189-198.

Other Sekelsky Publications

A. Laurencon. A. Purdy, J. Sekelsky J, R. Hawley, and T.T. Su (2003) Phenotypic analysis of separation-of-function alleles of mei-41, Drosophila ATM/ATR. Genetics 164: 589-601.

A.Z. Özsoy, J. Sekelsky, and S.W. Matson (2001) Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase. Nucleic Acids Res 29: 2986-2993.

J. Sekelsky, M.H. Brodsky, and K.C. Burtis (2000) DNA repair in Drosophila: Insights from the Drosophila genome sequence. J Cell Biology 150: F31-F36.

J. Sekelsky, K.J. Hollis, A.I. Eimerl, K.C. Burtis, and R.S. Hawley (2000) Nucleotide excision repair endonuclease genes in Drosophila melanogaster. Mutation Res 459: 219-228.

M.H. Brodsky, J. Sekelsky, G. Tsang, R.S. Hawley, and G.M. Rubin (2000) mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development. Genes Devel 14: 666-678.

K.S. McKim, J.K. Jang, J. Sekelsky, A. Laurencon, and R.S. Hawley (2000) mei-41 is required for precocious anaphase in Drosophila females. Chromosoma 109: 44-49.

L. Tisa, J. Sekelsky, and J. Adler (2000) Effects of organic antagonists of Ca²⁺, Na⁺, and K⁺ on chemotaxis and motility of Escherichia coli. J Bacteriol 182: 4856-4861.

J. Sekelsky, M.H. Brodsky, G.M. Rubin, and R.S. Hawley (1999) Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing. Nucleic Acids Res 27: 3762-3769.

J. Sekelsky, K.S. McKim, L. Messina, R.L. French, W.D. Hurley, T. Arbel, G.M. Chin, B. Deneen, S.J. Force, K.L. Hari, J.K. Jang, L. Madden, H.J. Matthies, D.B. Milliken, S.L. Page, A.D. Ring, S.M. Wayson, and R.S. Hawley (1999) Identification of novel Drosophila meiotic genes recovered in a P element screen. Genetics 152: 529-542.

J. Sekelsky, K.C. Burtis, and R.S. Hawley (1998) Damage control: The pleiotropy of DNA repair genes in Drosophila melanogaster. Genetics 148: 1587-1598.

K.S. McKim, B.L. Green-Marroquin, J. Sekelsky, G. Chin, C. Steinberg, R. Khodosh, and R.S. Hawley (1998) Meiotic synapsis in the absence of recombination. Science 279: 876-877.

J. Sekelsky and R.S. Hawley (1995) The bond between sisters. Cell 83: 157-160.

K.L. Hari, A. Santerre, J. Sekelsky, K.S. McKim, J.B. Boyd, and R.S. Hawley (1995) The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82: 815-821.

J. Sekelsky, K.S. McKim, G.M. Chin, and R.S. Hawley (1995) The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1. Genetics 141: 619-627.

J. Sekelsky, S. Newfeld, L.A. Raftery, E. Chartoff, and W.M. Gelbart (1995) Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139: 1347-1358.

M. Sanicola, J. Sekelsky, S. Elson, and W. Gelbart (1995) Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed. Genetics 139: 745-756.

B. Sager, J. Sekelsky, P. Matsumura, and J. Adler (1988) Use of a computer to assay motility in bacteria. Anal Biochem 173: 271-277.