John R. Pringle Biosketch and Publications

John R. Pringle Biosketch and Publications

Pringle, John R.
William Rand Kenan, Jr., Professor

Harvard University, Cambridge, MA

A.B.

1963

Mathematics

Harvard University, Cambridge, MA

Ph.D.

1971

Biology

University of Washington, Seattle, WA

Postdoct.

1970-73

Genetics

Swiss Federal Institute of Technology, Zürich

Postdoct.

1973-75

Microbiology

1960-1963	Harvard National Scholarship; General Motors National Scholarship; A.B. cum laude.
1964-1968	NSF Predoctoral Fellow; Teaching Fellow in Genetics; Resident Tutor in Biology.
1968-1970	Research Assistant in Biochemistry (with G. Guidotti, thesis advisor).
1970-1973	NIH Postdoctoral Fellow (studies of yeast cell cycle with L.H. Hartwell).
1973-1975	Research Associate (studies of yeast metabolism with A. Fiechter).
1975-1991	Assistant, Associate, and Full Professor of Biology, The University of Michigan.
1979	The University of Michigan Faculty Recognition Award.
1980-2000	Editorial Board, Molecular and Cellular Biology.
1982-present	Ad hoc member, NIH Study Sections: Genetics (3X), Biomedical Sciences (1X), Cellular & Molecular Basis of Disease (1X), Cell Biology and Physiology II (1X), and Special Study Sections (10X).
1984-1999	Editorial Board, Yeast.
1986-1987	Ad hoc member, ACS Microbiology & Virology Study Section (2X).
1988-1991	Editor, Cell Multiplication Section, Curr. Opin. Cell Biol.; Editorial Board, Developmental Genetics.
1989-1992	Member, ACS Microbiology & Virology Study Section (1991, Vice Chairman; 1992, Chairman).
1989 & 1991	Co-organizer, Cold Spring Harbor Laboratory Meetings on Yeast Cell Biology.
1991-present	William Rand Kenan, Jr., Professor of Biology, The University of North Carolina.
1994-1996	Member, ACS Scientific Advisory Committee on Personnel for Research.
1997-1999	Council, American Society for Microbiology.
1998-2002	Member, NIH Cell Development and Function 3 Study Section
1998-present	Fellow, American Academy of Microbiology; Member, Lineberger Comprehensive Cancer Center
1999-present	Council, American Society for Cell Biology
2000-present	Associate Editor, Molecular Biology of the Cell; NIH MERIT Award

Publications (1996-present)

1996 Fares, H.F., L. Goetsch & J.R. Pringle. Identification of a developmentally regulated septin and involvement of the septins in spore formation in S. cerevisiae. J. Cell Biol. 132: 399-411.

1996 Longtine, M.L., D.J. DeMarini, M.L. Valencik, O.S. Al-Awar, H. Fares, C. De Virgilio & J.R. Pringle. The septins: roles in cytokinesis and other processes. Curr. Opin. Cell Biol. 8: 106-119.

1996 Zahner, J.E., H.A. Harkins & J.R. Pringle. Genetic analysis of the bipolar pattern of bud-site-selection in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 1857-1870.

1996 Ohya, Y., B.E. Caplin, H. Qadota, M.F. Tibbetts, Y. Anraku, J.R. Pringle & M.S. Marshall. Mutational analysis of the b-subunit of yeast geranylgeranyl transferase I. Mol. Gen. Genet. 252: 1-10.

1996 Mack, D., K. Nishimura, B.K. Dennehey, T. Arbogast, J. Parkinson, A. Toh-e, J.R. Pringle, A. Bender & Y. Matsui. Identification of the bud emergence gene BEM4 and its interactions with Rho-type GTPases in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 4387-4395.

1996 Bi, E. & J.R. Pringle. ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 5264-5275.

1996 De Virgilio, C., D.J. DeMarini & J.R. Pringle. SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells. Microbiology 142: 2897-2905.

1996 Mathias, N., S.L. Johnson, M. Winey, A.E.M. Adams, L. Goetsch, J.R. Pringle, B. Byers & M.G. Goebl. Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S phase transition and identifies a conserved family of proteins. Mol. Cell. Biol. 16: 6634-6643.

1997 Amberg, D.C., J.E. Zahner, J.W. Mulholland, J.R. Pringle & D. Botstein. Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites. Mol. Biol. Cell 8: 729-753.

1997 Evangelista, M., K. Blundell, M.S. Longtine, C.J. Chow, N. Adames, J.R. Pringle, M. Peter & C. Boone. Bni1p, a yeast formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276: 118-122.

1997 Park, H.-O., E. Bi, J.R. Pringle & I. Herskowitz. Two active forms of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity. Proc. Natl. Acad. Sci. USA 94: 4463-4468.

1997 Pringle, J.R., J.R. Broach & E.W. Jones (eds.). The Molecular and Cellular Biology of the Yeast Saccharomyces. Cell Cycle and Cell Biology. Cold Spring Harbor Laboratory Press. 1131 pp.

1997 Lew, D.J., T. Weinert & J.R. Pringle. Cell cycle control in Saccharomyces cerevisiae. In The Molecular and Cellular Biology of the Yeast Saccharomyces. Cell Cycle and Cell Biology. (J.R. Pringle, J.R. Broach & E.W. Jones, eds.), pp. 607-695. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.

1997 DeMarini, D.J., A.E.M. Adams, H. Fares, C. De Virgilio, G. Valle, J. Chuang & J.R. Pringle. A septin-based hierarchy of proteins required for localized deposition of chitin in the Saccharomyces cerevisiae cell wall. J. Cell Biol. 139: 75-93.

1998 Bähler, J. & J.R. Pringle. Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis. Genes & Dev. 12: 1356-1370.

1998 Bähler, J., J.-Q. Wu, M.S. Longtine, N.G. Shah, A. McKenzie III, A.B. Steever, A. Wach, P. Philippsen & J.R. Pringle. Heterologous modules for efficient and versatile gene targeting in Schizosaccharomyces pombe. Yeast 14: 943-951.

1998 Longtine, M.S., A. McKenzie III, D.J. DeMarini, N.G. Shah, A. Wach, A. Brachat, P. Philippsen & J.R. Pringle. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953-961.

1998 Bi, E., P. Maddox, D.J. Lew, E.D. Salmon, J. McMillan, E. Yeh & J.R. Pringle. Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J. Cell Biol. 142: 1301-1312.

1998 Longtine, M.S., H. Fares & J.R. Pringle. Role of the yeast Gin4p protein kinase in septin assembly and the relationship between septin assembly and septin function. J. Cell Biol. 143: 719-736.

1998 Frazier, J.A., M.L. Wong, M.S. Longtine, J.R. Pringle, M. Mann, T.J. Mitchison & C. Field. Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. J. Cell Biol. 143: 737-750.

1998 Rodríguez-Medina, J.R., J.A. Cruz, P.W. Robbins, E. Bi & J.R. Pringle. Elevated expression of chitinase 1 and chitin synthase in myosin II-deficient Saccharomyces cerevisiae. Cell. Mol. Biol. 44: 919-925.

1998 Bähler, J., A.B. Steever, S. Wheatley, Y. Wang, J.R. Pringle, K.L. Gould & D. McCollum. Role of Polo kinase and Mid1p in determining the site of cell division in fission yeast. J. Cell Biol. 143: 1603-1616.

1999 Longtine, M.S. & J.R. Pringle. Septins. In Guidebook to the Cytoskeletal and Motor Proteins (T. Kreis & R. Vale, eds.), pp. 359-363. Oxford: Oxford University Press.

1999 McMillan, J.N., M.S. Longtine, R.A. Sia, C.L. Theesfeld, E. Bardes, J.R. Pringle & D.J. Lew. The morphogenesis check-point in S. cerevisiae: Cell-cycle control of Swe1p degradation by Hsl1p and Hsl7p. Mol. Cell. Biol. 19: 6929-6939.

1999 Hales, K.G., E. Bi, J.-Q. Wu, J.C. Adam, I.-C. Yu & J.R. Pringle. Cytokinesis: an emerging unified theory for eukaryotes? Curr. Opin. Cell Biol. 11: 717-725.

2000 Bi, E., J. Chiavetta, H. Chen, G. Chen, C. Chan & J.R. Pringle. Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol. Biol. Cell 11: 773-793.

2000 Longtine, M.S., C.L. Theesfeld, J.N. McMillan, E. Weaver, J.R. Pringle & D.J. Lew. Septin-dependent assembly of a cell-cycle-regulatory module in S. cerevisiae. Mol. Cell. Biol. 20: 4049-4061.

2000 Adam, J.C., J.R. Pringle & M.A. Peifer. Evidence for functional differentiation among Drosophila septins in cytokinesis and cellularization. Mol. Biol. Cell 11: 3123-3135..

2001 Wu, J.-Q., J. Bähler & J.R. Pringle. Roles of a fimbrin and an a-actinin-like protein in fission yeast cell polarization and cytokinesis. Mol. Biol. Cell 12: 1061-1077.

2001 Harkins, H.A., N. Pagé, L.R. Schenkman, C. De Virgilio, S. Shaw, H. Bussey & J.R. Pringle. Bud8p and Bud9p, proteins that may mark the sites of bipolar bud-site selection in yeast. Mol. Biol. Cell 12: 2497-2518.

2001 Drees, B., B. Sundin, E. Brazeau, J. Caviston, G. Chen, W. Guo, K. Kozminski, M. Lau, J. Moskow, A. Tong, L. Schenkman, A. McKenzie, P. Brennwald, M. Longtine, E. Bi., C. Chan, P. Novick, C. Boone, J. Pringle, T. Davis, S. Fields & D. Drubin. A protein interaction map for cell polarity. J. Cell Biol. 154: 549-571.

2001 Gladfelter, A., J.R. Pringle & D. Lew. The septin cortex at the yeast mother-bud neck. Curr. Opin. Microbiol. 4: 681-689.

2002 Shih, H.-P., K.G. Hales, J.R. Pringle & M. Peifer. Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila. J. Cell Sci. 115: 1259-1271.

2002 Schenkman, L.R., C. Caruso, N. Pagé & J.R. Pringle. Role of cell-cycle-regulated expression in the localization of spatial landmark proteins in yeast. J. Cell Biol. 156: 829-841.

2002 Lee, P., S. Song, H. Ro, C. Park, J. Lippincott, R. Li, J.R. Pringle, C. De Virgilio, M. Longtine & K.S. Lee. Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in S. cerevisiae. Mol. Cell. Biol. 22: 6906-6920.

2002 Macara, I. et al. (27 authors). Vertebrate septins nomenclature. Mol. Biol. Cell, in press.