Read about mathematical theories about the control of anatomical pattern formation
Textbook "Developmental Biology" Scott Gilbert SEVENTH EDITION
Lectures Mon-Wed-Fri 9-9:50
Harris Office room 104 Wilson Hall, Harris Office Hours: MWF 10-12; Friday 2-5
e-mail: akharris@bio.unc.edu
Tel.966-1230
| 1) Wed Jan 7 | What happens in development; fertilization, cleavage, differentiation, rearrangements | pp 3-8 | ||
| 2) Fri Jan 9 | Compare embryology of sea urchin, frog, bird & mammal; similarities & differences | pp 9-16, web page | ||
| 3) Mon Jan 12 | Continuation of Lecture 2 Read about mathematical theories about the control of anatomical pattern formation | pp.8-22, and pages 64-69 | ||
| 4) Wed Jan 14 | Guest lecture: Unicellular organisms --> Multicellular organisms | web page, read pages 33-38 | ||
| 5) Fri. Jan 16 | Guest lecture: Dictyostelium (slime molds: another example of 1-cell->many cell | web page, read pp 39-44 | ||
| Mon. Jan 19 | Holiday in honor of Rev Martin Luther King jr. | |||
| 6) Wed Jan. 21 | The molecular genetic approach to embryology | web page, Chapter Four pages 81-106 | ||
| 7) Fri. Jan. 23 | Mechanisms of differential gene expression | web page, Chapter Five pp. 107-142 | ||
| 8) Mon Jan. 26 | Control of gene expression by cell-cell signals:="embryological induction" [cancelled, snow] | Chapter Six pp 143-180 | ||
| 9) Wed Jan. 28 | Why do dissociated cells sort out & reform tissues? What is its biological significance? [cancelled, snow] | pp 70-77 | ||
| 10) Fri. Jan. 30 | makeup for Jan. 26 & 28. | web page | ||
| 11) | First Exam Wednesday Feb. 4 | REVIEW QUESTIONS | ||
| 12) Fri Feb 6 | Fertilization | web page, Chapter Seven 183-219 | ||
| ******** | ||||
| new web pages posted February 20th-27th: | ||||
| Differences Between Embryos | ||||
| Fly Genes, Hox Genes in Other Organisms | ||||
| Embryonic Development in Amphibians | ||||
| Review Questions for Second Exam | ||||
| ******** | ||||
| 13) | Differences between embryos of sea urchins, snails, sea squirts & nematodes | web page, Chapter Eight pp. 221-262 | ||
| 14) | The genes that control insect development | web page, Chapter Nine pp. 305-263 | ||
| 15) | Embryonic development of frogs and salamanders | web page, Chapter Ten pp. 305-343 | ||
| Second Exam Monday March 1 | review questions | |||
| 16) | Special features of development of fish embryos | web page, Chapter Eleven pp 345-354 | ||
| Bird and reptile embryonic development | More Chapter Eleven 356-363 | |||
| Mammal development | 363-388 | |||
| Mon. Mar 8 - Fri. Mar 12 | Spring vacation | |||
| ******** | ||||
| How do the Hox genes control axis development? And what controls them!? | pp 375-388 | |||
| 17) Wed. March 17 | Ectodermal organs | web page, Chapter Twelve Pages 391-425 | ||
| Neural crest | pp 427-442 | |||
| Development of plants, as an interesting contrast to animal embryos. | Chapter Twenty pp 649-681 | |||
| More on development of higher plants | ||||
| What mechanisms control the proper "wiring" of the nervous system? | pp. 442-463 | |||
| More on the wiring of the nervous system, especially eye to brain connections. | ||||
| Mesoderm: Notochord, Somites and Intermediate Mesoderm | Chapter Fourteen pages 465-489 | |||
| Lateral plate mesoderm, coelom, uterus and heart | Chapter Fifteen 491-509?? | |||
| Endodermal organs | Pages 510-515 | |||
| Extraembryonic membranes | pages 516-517 | |||
| Legs, wings, arms, maybe even fins | Chapter Sixteen pp 523-546 | |||
| Review for third exam | ||||
| ******** | ||||
| web pages to review for third exam | ||||
| Embryonic Development in Fish | ||||
| Bird and Mammal Embryology | ||||
| March 17-22 | Ectodermal Organs | |||
| Mesoderm | ||||
| Fri. March 26 | Stem cells | |||
| Mon. March 29 | Nervous system | |||
| Mon. March 29 | REVIEW QUESTIONS | |||
| ******** | ||||
| Fri Apr. 2 | Third Exam | |||
| ******** | ||||
| more web pages | ||||
| Mon. April 5 | Mechanical forces, geometrical shapes, and asymmetry | |||
| Mechanics page from last year | ||||
| Heart and circulatory system | ||||
| Limb bud development | ||||
| Kidneys and male sex ducts | ||||
| Endoderm and Skeleton | ||||
| final set of review questions | ||||
| ******** | ||||
| Sex determination (=mechanisms that cause tissues to become male or female) | pp 547-573 | |||
| Metamorphosis (tadpole --> frog, caterpillar->butterfly, maggot -> fly) | pp 575-592 | |||
| Regeneration (why can salamanders regenerate legs, & we regenerate liver? | pp 592-601 | |||
| Aging (maybe it's programmed self-destruction, instead of wearing out? | pp 601-606 | |||
| Primordial germ cells and germ plasm | Pages 613-646 | |||
| Medical aspects of embryonic development | Chapter Twenty-One pp. 683-719 | |||
| Environmental effects on embryonic development | Chapter Twenty-Two pp 721-749 | |||
| "Evo-Devo" = Evolution of developmental mechanisms | Chapter Twenty-Three pp 751-784 | |||
| Mon. Apr. 26, 8 Am | Final Exam |