Some recent papers published by the Bautch Lab:

Chappell JC Taylor SM Ferrara N, Bautch VL. (2009). Local guidance of emerging vessel sprouts requires soluble Flt-1. Dev Cell 17, 377-386. doi:10.1016/j.devcel2009.07.011. Cover Photo. (PDF link manuscript).

Bautch VL and James JM. (2009). Neurovascular development: the beginning of a beautiful friendship. Cell Adh. Migr. 3, 199-204. (PDF link manuscript).

Bautch VL. (2009). Endothelial cells form a phalanx to block tumor metastasis. Cell 136, 810-812. (Commentary) (PDF link commentary).

James JM, Gewolb C, Bautch VL. (2009). Neurovascular development utilizes VEGF-A signaling to regulate blood vessel ingression into the neural tube. Development 136, 833-841 (PDF link to manuscript).

Zeng G and Bautch VL. (2009). Differentiation and dynamic analysis of primitive vessels from ES cells. In Methods in Molecular Medicine, Vol. 482, Regenerative Medicine (eds. J. Audet and W.L. Stanford), pp. 333-344, New Jersey: Humana Press.

Bautch VL. (2008). Ninein leads the way in vessel sprouting. Arterioscler Thromb Vasc Biol 28, 2094-2095 (Commentary) (PDF link to commentary).

Kappas NC*, Zeng G*, Chappell JC, Kearney JB, Hazarika S, Kallianos KG, Patterson C, Annex BH, Bautch VL. (2008). The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. J Cell Biol 181, 847-858. * = Co first-authors. (PDF link paper).

Loureiro RMB, Monaco K-A, Kearney JB, Blickarz-Durand CE, Kirby S, Inamdar MS, Bautch VL. (2008). CSF-1 is required for early embryonic macrophage development: characterization of the csfmop/csfmop mutaton in ES cell-derived macrophages. Brit J Haematol 141, 739-742.

Hartnett ME, Martiniuk D, Sutton DS, Byfield G, Geisen P, Zeng G, Bautch VL. (2008). Neurtralizing VEGF decreases tortuosity and rescues endothelial division orientation in arterioles and veins in a rat model of ROP. Invest Opthalmol Vis Sci 49, 3107-3114.

Rylova SN, Randhawa PK, Bautch VL. (2008). In vitro differentiation of mouse embryonic stem cells into primitive blood vessels. In Meth Enzymol, Vol. 443, Angiogenesis: In Vitro Systems (ed. D Cheresh), pp. 103-117, San Diego CA: Elsevier Academic Press.

Bautch, VL. (2007). Animal models of vascular development and endothelial cell biology. In Source Book of Models for Biomedical Research, (ed. PM Conn) pp. 355-360, New Jersey: Humana Press.

Kappas, NC and Bautch, VL . (2007). Maintenance and in vitro differentiation of mouse embryonic stem cells to form blood vessels. In Current Protocols in Cell Biology, (ed J.S. Bonifacino et al.). pp. 23.3.1-23.3.20 . John Wiley & Sons, Inc.

Zeng G, Taylor SM, McColm JR, Kappas NC, Kearney JB, Williams LH, Hartnett ME and Bautch, VL . (2007). Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation. Blood 109, 1345-1352. This article was chosen as a Plenary Paper (definitive manuscripts of exceptional scientific importance) and the subject of a commentary: Claesson-Welsh L (2007). Endothelial cells in line. Blood 109, 1343-1344. (PDF link paper) (PDF link commentary).

Wang, H., Charles, P.C., Wu, Y., Ren, R., Pi, X., Moser, M., Barshishat-Kupper, M., Rubin, J.S., Perou, C., Bautch, V. , and Patterson, C. (2006). Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cells. Circ Res 98, 1331-1339. (PDF link)

Roberts, D.M., Anderson, A.L., Hidaka, M., Swetenburg, R.L., Patterson, C., Stanford, W.L., and Bautch, V.L. (2004). A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Mol Cell Biol 24, 10515-10528. Cover photo. (PDF link)

Hogan, K.A. and Bautch, V.L. (2004). Blood vessel patterning at the embryonic midline. Curr Topics Dev Biol. 62, 55-85.

Bautch, V.L. , and Ambler, C.A. (2004). Assembly and patterning of vertebrate blood vessels. Trends Cardiovasc Med. 14, 138-143. (PDF link)

Kearney, J.B.*, Kappas, N.C.*, Ellerstrom, C., DiPaola, F.W., and Bautch, V.L. (2004). The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis. Blood 103, 4527-4535. (*= co-first authors). This article and another were subjects of a short commentary: Stacker, SA and Achen, MG. (2004). Inside Blood: VEGF receptors branch into new areas. Blood 103, 4379-4380. (PDF link)

Hogan, K.A.*, Ambler, C.A.*, Chapman, D.L., and Bautch, V.L. (2004). The neural tube patterns vessels developmentally using the VEGF signaling pathway. Development 131, 1503-1513. (*= co-first authors). This article was the subject of a short commentary: Bradbury, J. (2004). In this issue: hooking up the blood supply, Development 131. (PDF link)

Roberts, D.M., Kearney, J.B., Johnson, J.H., Rosenberg, M.P., Kumar, R., and Bautch, V.L. (2004). The VEGF receptor flt-1 (VEGFR-1) modulates flk-1 (VEGFR-2) signaling during blood vessel formation. Am. J. Path. 164, 1531-1535. (PDF link)

Kearney, J.B., and Bautch, V.L. (2003). In vitro differentiation of mouse ES cells: hematopoietic and vascular development. In Meth. Enzymol. vol. 365, Differentiation of Embryonic Stem Cells (eds. P.M. Wassarman and G.M Keller), pp. 83-98, San Deigo CA: Elsevier Academic Press.

Ambler, C.A., Schmunk, G.M., and Bautch, V.L. (2003). Stem cell-derived endothelial cells/progenitors migrate and pattern in the embryo using the VEGF signaling pathway. Dev. Biol. 257, 205-219. (PDF link).

Kearney, J.B., Ambler, C.A., Monaco, K-A., Johnson, N., Rapoport, R., and Bautch, V.L. (2002).  The VEGF receptor flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99, 2397-2407. Cover photo. (PDF link ).

Ambler, C.A., Nowicki, J.L., Burke, A.C., and Bautch, V.L. (2001).  Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts. Dev. Biol. 234, 352-364. (PDF link).

Bautch, V.L., Redick, S. D., Scalia, A., Harmaty, M., Carmeliet, P, and Rapoport, R. (2000).  Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A. Blood 95, 1979-1987. (PDF link).

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