Links to some recent papers published by the Bautch Lab:

Bautch, VL. (2007). Animal models of vascular development and endothelial cell biology. In Source Book of Models for Biomedical Research, (ed. PM Conn) pp. , New Jersey: Humana Press. (In Press).

Zeng, G and Bautch, V.L . (2007). Differentiation and dynamic analysis of primitive vessels from ES cells In Methods in Molecular Medicine, Vol. , Regenerative medicine (ed. J. Audet and W.L. Stanford). pp. , New Jersey: Humana Press. (In Press).

Kappas, NC and Bautch, VL . (2007). Maintenance and in vitro differentiation of mouse embryonic stem cells to form blood vessels. In Current Protocols in Cell Biology, (ed J.S. Bonifacino et al.). pp. 23.3.1-23.3.20 . John Wiley & Sons, Inc.

Zeng G, Taylor SM, McColm JR, Kappas NC, Kearney JB, Williams LH, Hartnett ME and Bautch, VL . (2007). Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation. Blood 109, 1345-1352. This article was chosen as a Plenary Paper (definitive manuscripts of exceptional scientific importance) and the subject of a commentary: Claesson-Welsh L (2007). Endothelial cells in line. Blood 109, 1343-1344. (PDF link paper) (PDF link commentary).

Wang H, Gilner JB, Bautch VL , Wang DZ, Wainwright BJ, Kirby SL and Patterson C. (2007). Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial and cardiac lineages in embryoid bodies. J Biol Chem 282, 782-791. (PDF link)

Wang, H., Charles, P.C., Wu, Y., Ren, R., Pi, X., Moser, M., Barshishat-Kupper, M., Rubin, J.S., Perou, C., Bautch, V. , and Patterson, C. (2006). Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cells. Circ Res 98, 1331-1339. (PDF link)

Roberts, D.M., Anderson, A.L., Hidaka, M., Swetenburg, R.L., Patterson, C., Stanford, W.L., and Bautch, V.L. (2004). A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Mol Cell Biol 24, 10515-10528. Cover photo. (PDF link)

Hogan, K.A. and Bautch, V.L. (2004). Blood vessel patterning at the embryonic midline. Curr Topics Dev Biol. 62, 55-85.

Bautch, V.L. , and Ambler, C.A. (2004). Assembly and patterning of vertebrate blood vessels. Trends Cardiovasc Med. 14, 138-143. (PDF link)

Kearney, J.B.*, Kappas, N.C.*, Ellerstrom, C., DiPaola, F.W., and Bautch, V.L. (2004). The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis. Blood 103, 4527-4535. (*= co-first authors). This article and another were subjects of a short commentary: Stacker, SA and Achen, MG. (2004). Inside Blood: VEGF receptors branch into new areas. Blood 103, 4379-4380. (PDF link)

Hogan, K.A.*, Ambler, C.A.*, Chapman, D.L., and Bautch, V.L. (2004). The neural tube patterns vessels developmentally using the VEGF signaling pathway. Development 131, 1503-1513. (*= co-first authors). This article was the subject of a short commentary: Bradbury, J. (2004). In this issue: hooking up the blood supply, Development 131. (PDF link)

Roberts, D.M., Kearney, J.B., Johnson, J.H., Rosenberg, M.P., Kumar, R., and Bautch, V.L. (2004). The VEGF receptor flt-1 (VEGFR-1) modulates flk-1 (VEGFR-2) signaling during blood vessel formation. Am. J. Path. 164, 1531-1535. (PDF link)

Kearney, J.B., and Bautch, V.L. (2003). In vitro differentiation of mouse ES cells: hematopoietic and vascular development. In Meth. Enzymol. vol. 365, Differentiation of Embryonic Stem Cells (eds. P.M. Wassarman and G.M Keller), pp. 83-98, San Deigo CA: Elsevier Academic Press.

Ambler, C.A., Schmunk, G.M., and Bautch, V.L. (2003). Stem cell-derived endothelial cells/progenitors migrate and pattern in the embryo using the VEGF signaling pathway. Dev. Biol. 257, 205-219. (PDF link).

Kearney, J.B., Ambler, C.A., Monaco, K-A., Johnson, N., Rapoport, R., and Bautch, V.L. (2002).  The VEGF receptor flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99, 2397-2407. Cover photo. (PDF link ).

Bautch, V.L. (2001). Embryonic stem cell differentiation and the vascular lineage. In Methods in Molecular Biology, Vol. 185, Embryonic stem cells: methods and protocols (ed. K. Turksen). pp. 117-125, New Jersey: Humana Press.

Ambler, C.A., Nowicki, J.L., Burke, A.C., and Bautch, V.L. (2001).  Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts. Dev. Biol. 234, 352-364. (PDF link).

Bautch, V.L., Redick, S. D., Scalia, A., Harmaty, M., Carmeliet, P, and Rapoport, R. (2000).  Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A. Blood 95, 1979-1987. (PDF link).

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