Department of Biology

Albert S. Baldwin, Jr. References

Steinbrecher KA, Wilson W 3rd, Cogswell PC, Baldwin AS. Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription. Mol Cell Biol. 2005 Oct;25(19):8444-55.

Sitcheran R, Gupta P, Fisher PB, Baldwin AS. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. EMBO J. 2005 Feb 9;24(3):510-20.

Ventura JJ, Cogswell P, Flavell RA, Baldwin AS Jr, Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev. 2004 Dec 1;18(23):2905-15.

Hanson JL, Hawke NA, Kashatus D, Baldwin AS. The nuclear factor kappaB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer Res. 2004 Oct 15;64(20):7248-55.

Anest V, Cogswell PC, Baldwin AS Jr. IkappaB kinase alpha and p65/RelA contribute to optimal epidermal growth factor-induced c-fos gene expression independent of IkappaBalpha degradation. J Biol Chem. 2004 Jul 23;279(30):31183-9

Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS Jr, Tisch R. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood. 2004 Aug 15;104(4):1100-9

Baldwin AS. NF kappa B: biology and pathology--Keystone Symposium. 11-16 January 2004, Snowbird, UT, USA. IDrugs. 2004 Mar;7(3):215-6

Baer JT, Du Laney TV, Wyrick PB, McCain AS, Fischer TA, Merricks EP, Baldwin AS, Nichols TC. Nuclear factor-kappaB activation in endothelium by Chlamydia pneumoniae without active infection. J Infect Dis. 2003 Oct 15;188(8):1094-7

Sitcheran R, Cogswell PC, Baldwin AS Jr. NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism.Genes Dev. 2003 Oct 1;17(19):2368-73.

Hanson JL, Anest V, Reuther-Madrid J, Baldwin AS. Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathways.J Biol Chem. 2003 Sep 12;278(37):34910-7.

Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature. 2003 Jun 5;423(6940):659-63.

Madrid LV, Baldwin AS Jr. Regulation of NF-kappaB by oncoproteins and tumor suppressor proteins. Methods Mol Biol. 2003;223:523-32. Review.

Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS Jr, Tisch R.  NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. J Immunol. 2003 Feb 15;170(4):1770-80.

Cogswell PC, Kashatus DF, Keifer JA, Guttridge DC, Reuther JY, Bristow C, Roy S, Nicholson DW, Baldwin AS Jr. NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B. J Biol Chem. 2003 Jan 31;278(5):2963-8.

Sitcheran, R., P. Cogswell, and A. Baldwin (2003). NF-kB mediates inhibition of mesenchymal cell differentiation through a post-transcriptional gene silencing mechanism. Genes and Development, in press.

 Anest, V., J. Hanson, P. Cogswell, K. Steinbrecher, B. Strahl, and A. Baldwin (2003). A nucleosomal function for IKKa in NF-kB-dependent gene expression. Nature 423:  659-663.

 Hanson, J., V. Anest, and A. Baldwin (2003). Oncoprotein suppression of NF-kB activation by TNF is independent of Raf-controlled pathways. J. Biol. Chem., in press.

 Reuther-Madrid, J., D. Kashatus, S. Chen, X. Li, J. Westwick, R. Davis, H. S. Earp, C.-Y. Wang, and A. Baldwin (2002). The p65/RelA subunit of NF-kB suppresses the sustained, antiapoptotic activity of Jun kinase induced by TNF. Mol. Cell. Biol. 22: 8175-8183.

 Orlowski, R. and A. Baldwin (2002). NF-kB as a therapeutic target in cancer. Trends in Molecular Medicine 8: 385-389.


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