• Current position: Director, Women's Cancer Biology, Women's Cancer Research Institute
  Cedars-Sinai Medical Center
• Assistant Professor, MGH Cancer Center/Harvard Med School
• Postdoctoral fellow with Dr. Harold Varmus, Former director of NIH/Now head of Memorial Sloan Kettering Cancer Center
• Recipient of a Susan G. Komen Breast Cancer Foundation Post-doctoral Fellowship (one of only eleven awarded that year)

• Cox, R.T., Pai, L.-M., Miller, J.R., Orsulic, S., Stein, J., McCormick, C.A., Audeh, Y., Wang, W., Moon, R.T., and Peifer, M. (1999). Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development 126, 1327-1335.
• Pai, L.-M., Orsulic, S., Bejsovec, A. and Peifer, M. (1997). Negative regulation of Armadillo, a Wingless effector in Drosophila . Development 124, 2255-2266.
• Orsulic, S., and Peifer, M. (1996). Wingless lands at last. Current Biology 6, 1363-1367.
• Orsulic, S., and Peifer, M. (1996). An in vivo structure-function study of Armadillo, the ß-catenin homolog, reveals both separate and overlapping regions of the protein required for cell adhesion and for Wingless signaling. J. Cell Biol. 134, 1283-1301.
• Orsulic, S., and Peifer, M. (1994). A method to stain nuclei of Drosophila for confocal microscopy. Biotechniques 16, 441-447.
• Peifer, M., Orsulic, S., Pai, L.-M., and Loureiro, J. (1993). A model system for cell adhesion and signal transduction in Drosophila (Review). 1993 Development Suppl. 163-176.
• Peifer, M., Orsulic, S., Sweeton, D., and Wieschaus, E. (1993). A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis. Development 118, 1191-1207.

• Publications from Peifer lab
  • Cox, R.T., Pai, L.-M., Kirkpatrick, C., Stein, J., and Peifer, M. (1999). Roles of the C-terminus of Armadillo in Wingless signaling in Drosophila. Genetics 153: 319-332.
  • Cox, R.T., Pai, L.-M.(co-first author), Miller, J.R., Orsulic, S., Stein, J., McCormick, C.A., Audeh, Y., Wang, W., Moon, R.T., and Peifer, M. (1999). Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development 126: 1327-1335.
  • Pai, L.-M., Orsulic, S., Bejsovec, A. and Peifer, M. (1997). Negative regulation of Armadillo, a Wingless effector in Drosophila . Development 124: 2255-2266.
  • Pai, L.-M., Kirkpatrick, C., Blanton, J., Oda, H., Takeichi, M., and Peifer, M. (1996). -catenin and DE-cadherin occupy distinct binding sites on Drosophila Armadillo that differ substantially in size. J. Biol. Chem. 271: 32411-32420.
  • Peifer, M., Pai, L.-M., and Casey, M. (1994). Phosphorylation of the Drosophila adhesive junction protein Armadillo: roles for Wingless signal and Zeste white-3 kinase. Dev. Biol. 166: 543-556.
  • Peifer, M., Orsulic, S., Pai, L.-M., and Loureiro, J. (1993). A model system for cell adhesion and signal transduction in Drosophila (Review). 1993 Development Suppl. 163-176.

• Grevengoed, E.E., Loureiro, J., Jesse T., and Peifer, M. (2001)  Abelson kinase regulates epithelial morphogenesis in Drosophila.  Journal of Cell Biology 155:1185-1197
• Loureiro, J., Akong, K., Cayirlioglu, P., Baltus, A.E., DiAntonio, A., and Peifer, M. (2001) In vivo tests of Armadillo/ß-catenin’s proposed roles in cell migration and process extension suggest that these roles are tissue specific. Developmental Biology 235: 33-44.
• Cox, R.T., McEwen, D.G., Myster, D.G., Duronio, R.J., Loureiro, J., and Peifer, M. (2000). A screen for mutations that suppress the phenotype of Drosophila armadillo, the b -catenin homolog. Genetics 155: 1725-1740.
• Loureiro, J. (1999). Wnt signaling: A quick guide. Current Biology 9: R4.
• Loureiro, J., and Peifer, M. (1998). The roles of Armadillo, a Drosophila catenin, during central nervous system development. Current Biology 8: 622-632.
• van de Wetering, M., Cavallo, R., Dooijes, D., van Beest, M., van Es, J., Loureiro, J., Ypma, A., Hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M., and Clevers, H. (1997). Armadillo co-activates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789-799.
• Peifer, M., Orsulic, S., Pai, L.-M., and Loureiro, J. (1993). A model system for cell adhesion and signal transduction in Drosophila (Review). 1993 Development Suppl. 163-176.

• Publications from Peifer lab
  • McEwen, D.G., Cox, R.T. (co-first author), and Peifer, M. (2000) The canonical Wg and JNK signaling cascades function in parallel to promote both dorsal closure and ventral patterning. Development 127: 3607-3617.
  • Cox, R.T., McEwen, D.G., Myster, D.G., Duronio, R.J., Loureiro, J., and Peifer, M. (2000). A screen for mutations that suppress the phenotype of Drosophila armadillo, the b -catenin homolog. Genetics 155: 1725-1740.
  • Cox, R.T., Pai, L.-M., Miller, J.R., Orsulic, S., Stein, J., McCormick, C.A., Audeh, Y., Wang, W., Moon, R.T., and Peifer, M. (1999). Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development 126: 1327-1335.
  • Cox, R.T., Pai, L.-M., Kirkpatrick, C., Stein, J., and Peifer, M. (1999). Roles of the C-terminus of Armadillo in Wingless signaling in Drosophila. Genetics 153: 319-332.
  • Cox, R.T., and Peifer, M. (1998). Wingless/Wnt signaling: The inconvenient complexitites of life. Current Biology 8: R140-R144.
  • Cavallo, R.A., Cox, R.T. (co-first author), Moline, M.M., Roose, J., Polevoy, G.A., Clevers, H., Peifer, M., and Bejsovec, A. (1998). Drosophila TCF and Groucho interact to repress Wingless signaling activity. Nature 395: 604-608.
  • Cox, R., Kirkpatrick, C., and Peifer, M. (1996). Armadillo is required for adherens junction assembly, cell polarity and morphogenesis during Drosophila embryogenesis, J. Cell Biol. 134: 133-148.

• Current position:Medical Science Liaison, 3M Pharmaceuticals
• Awarded Jane Coffin Childs Postdoctoral Fellowship

• Myster, S.H., Wang, F., Cavallo, R., Christian, W., Bhotika, S., Anderson, C.T., and Peifer, M. (2004). Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: A window on the heterochromatin-euchromatin junction. Genetics, in press.
• Myster, S.H., Cavallo, R., Anderson, C.T., Fox, D.T., and Peifer, M.  (2003)  Drosophila p120catenin plays an important supporting role in cell adhesion but is not an essential adherens junction component.  Journal of Cell Biology 160, 433-449.
• Lu, Q., Paredes, M., Medina, M., Zhou, J., Cavallo, R. , Peifer, M., Orecchio, L. and Kosik, K.S. (1999). Delta-catenin, an adhesive junction-associated protein which promotes cell scattering. J. Cell Biol. 144: 519-532.
• Cavallo, R.A., Cox, R.T., Moline, M.M., Roose, J., Polevoy, G.A., Clevers, H., Peifer, M., and Bejsovec, A. (1998). Drosophila TCF and Groucho interact to repress Wingless signaling activity. Nature 395: 604-608.
• Cavallo, R., Rubenstein, D., and Peifer, M. (1997). Armadillo and dTCF: A marriage made in the nucleus. Curr. Opin. Genet. Devel. 7: 459-466.
• van de Wetering, M., Cavallo, R. (co-first author) , Dooijes, D., van Beest, M., van Es, J., Loureiro, J., Ypma, A., Hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M., and Clevers, H. (1997). Armadillo co-activates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789-799.

• Current position: Child Health Associate - Physician Assistant student at the University of Colorado Health Sciences Center
• Postdoctoral Fellow with Dr. Deb Andrew at Johns Hopkins University
• Awarded NIH Postdoctoral Fellowship

• McCartney BM, McEwen DG, Grevengoed E, Maddox P, Bejsovec A, Peifer M. (2001) Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nature Cell Biology 3: 933-8.
  
• Grevengoed EE, Loureiro JJ, Jesse TL, Peifer M. (2001) Abelson kinase regulates epithelial morphogenesis in Drosophila. Journal of Cell Biology 155: 1185-98.
  
• Akong K, Grevengoed EE, Price MH, McCartney BM, Hayden MA, DeNofrio JC, and Peifer M. (2002) Drosophila APC2 and APC1 play overlapping roles in Wingless signaling in the embryo and imaginal discs. Developmental Biology. 250: 91-100.
  
• Grevengoed EE, Peifer, M (2003). Cytoskeletal Connections: Building strong cells in new ways. Current Biology. 13: R568-R570.
  
• Grevengoed EE, Fox D, Gates J., Peifer, M (2003). Balancing different types of actin polymerization at distinct sites: Roles for Abelson kinase and Enabled. Journal of Cell Biology 163, 1267-1280.

• Current position:Resident in Pediatric Medicine, UCSD

• Rusan, N.M., Akong, K., and Peifer, M. (2008). Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowthand axon targeting? Journal of Cell Biology 183, 203-212..
• Hayden, M.A., Akong, K., and Peifer, M. (2007). Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Developmental Biology 305, 358-376.
• Akong, K., McCartney, B.M., and Peifer, M. (2002). Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Developmental Biology 250, 71-90.
  
• Akong, K., Grevengoed, E.E., Price, M.H., McCartney, B.M., Hayden, M.A., DeNofrio, J.C., and Peifer, M. (2002). Drosophila APC2 and APC1 play overlapping roles in Wingless signaling in the embryo and imaginal discs. Developmental Biology 250, 91-100.
  
• Loureiro, J.J., Akong, K., Cayirlioglu, P., Baltus, A.E., DiAntonio, A., and Peifer, M. (2001) Activated Armadillo/ß-catenin does not play a general role in cell migration and process extension in Drosophila. Developmental Biology 235: 33-44.

• Current position:Postdoctoral Fellow, Dr. Alan Spradling, Carnegie Institution, Baltimore MD

• Awarded Jane Coffin Childs Postdoctoral Fellowship

• Fox, D.T., and Peifer, M. (2007). Abelson kinase and RhoGEF2 regulate actin organization during cell constriction in Drosophila. Development 134, 567-578.
• Stevens, T L., Rogers, E M., Koontz, L. M. , Fox, D. T., Homem, C. C.F., Nowotarski, S. H., Artabazon, N. B., and Peifer, M. (2008). Using Bcr-Abl to examine mechanisms by which Abl kinase regulates morphogenesis in Drosophila. Molecular Biology of the Cell 19, 378-393.
  
• Fox, D.T.,and Peifer, M. (2007). Cell adhesion: Separation of p120's powers? Current Biology 17, R24-R27.
  
• Fox, D.T., Homem, C.C.F., Myster, S.H., Wang, F., Bain, E.E., and Peifer, M. (2005). Rho1 Regulates Drosophila Adherens Junctions Independently of p120ctn. Development 132, 4819-4831.

• Grevengoed E.E., Fox D.T., Gates J., Peifer, M. (2003). Balancing different types of actin polymerization at distinct sites: Roles for Abelson kinase and Enabled. Journal of Cell Biology, 163, 1267-1280.

• Myster, S.H.,, Cavallo, R., Anderson, C.T., Fox, D.T.. and Peifer, M. (2003). Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component. Journal of Cell Biology160 433-449.

• Current position:Postdoctoral Fellow, Dr. Akira Chiba, Univ. of Illinois, Champaign-Urbana IL

• Hayden, M.A., Akong, K., and Peifer, M. (2007). Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Developmental Biology 305, 358-376.

• McCartney BM, Price MH, Webb RL, Hayden MA, Holot LM, Zhou M, Bejsovec A, Peifer M. (2006). Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development 133:2407-18

• Akong, K., Grevengoed, E.E., Price, M.H., McCartney, B.M., Hayden, M.A., DeNofrio, J.C., and Peifer, M. (2002). Drosophila APC2 and APC1 play overlapping roles in Wingless signaling in the embryo and imaginal discs. Developmental Biology 250, 91-100.

Rachel Cox:

• 1997 ASCB Travel Award
• 1997 Sarah Graham Kenan/Hobgood Fellowship (Award for the best Ph.D. students in the Curriculum in Genetics and Molecular Biology)
• 1998 Biorad/ASCB Travel Award