The final product of our countless hours of work -- lots of publications.
Most are available in PDF format for your downloading pleasure.


 

Yeh, E., Haase, J., Paliulis, L., Joglekar, A., Bond, L., Bouck, D., Salmon, E.D., and Bloom, K.(2008) Pericentric Chromatin Is Organized into an Intramolecular Loop in Mitosis. Current Biology 18:81-90.


Gardner, M., Haase, J., Karthikeyan, M., Molk, J., Anderson, M., Joglekar, A., O'Toole, E., Winey, M., Salmon, E.D., Odde, D., and Bloom, K. (2008) The microtubule-based motor Kar3 and plus end–binding protein Bim1 provide structural support for the anaphase spindle  Journal of Cell Biology  180:91-100.


Gardner, M., Odde, D., and Bloom, K. (2007) Hypothesis testing via integrated computer modeling and digital fluorescence microscopy  Methods 41:232-237

Bouck, D.C. and Bloom K. (2007) Pericentric chromatin is an elastic component of the mitotic spindle. Curr. Biology 17:1-8


Dotiwala, F., Haase, J., Arbel-Eden, A., Bloom, K., and Haber, J. (2007) The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage.  PNAS  104:  11358-11363


Shimogawa M.M., Graczyk, B., Gardner, M.K., Francis, S.E., Ess, M., Ruse, C., Niessen, S., Muller, E., Yoder, T.J., Molk, J.N, Bloom, K., Yates, J.R., III, Odde, D.J., and Davis, T.N. (2006) Mps1 Phosphorylation of the Kinetochore Component Dam1 Couples Kinetochores to Microtubule Plus Ends at Metaphase  Current Biology 16:1489–1501.

Pearson C.G., Gardner M.K., Paliulis L.V., Salmon E.D., Odde D.J., and Bloom K. (2006)
Measuring Nanometer Scale Gradients in Spindle Microtubule Dynamics Using Model Convolution Microscopy  Mol. Biol. Cell  10.1091/mbc.E06-04-0312


Joglekar, A.P., Bouck, D.C., Molk, J.N, Bloom, K.S., and Salmon, E.D. (2006) Molecular Architecture of a Kinetochore-microtubule attachment site  Nature Cell Biology  8:581-585.


Fisher, J.K., Cribb, J., Desai, K.V., Vicci, L., Wilde, B., Keller, K., Taylor II, R.M., Haase, J., Bloom, K., O'Brien, E.T., and Superfine, R. (2006) Thin-foil magnetic force system for high-numerical-aperture microscopy  Review of Scientific Instruments  77:023702.1-023702.9.


Bloom, K., Sharma, Shantanu, and Dokholyan, Nikolay V. (2006) The path of DNA in the kinetochore  Current Biology  16:R276-R278.


Molk, J.N., Salmon, E.D., and Bloom, K. (2006) Nuclear congression is driven by cytoplasmic
microtubule plus end interactions in S. cerevisiae
  Journal of Cell Biology  172:27-39.


Gardner, M.K., Pearson, C.G., Sprague, B.L., Zarzar, T.R., Bloom, K., Salmon, E.D., and Odde, D.J. (2005) Tension-Dependent Regulation of Microtubule Dynamics at Kinetochores Can Explain Metaphase Congression in Yeast  Molecular Biology of the Cell  16:3764-3775.


Jones, M.H., Huneycutt, B.J., Pearson, C.G., Zhang, C., Morgan, G., Shokat, K., Bloom, K., and Winey, M. (2005) Chemical Genetics Reveals a Role for Mps1 Kinase in Kinetochore Attachment during Mitosis  Current Biology 15:160-165.


Bouck, David C. and Bloom, Kerry S. (2005) The kinetochore protein Ndc10p is required for spindle stability and cytokinesis in yeast  PNAS 102:5408–5413.


Lobachev, K., Vitriol, E., Stemple, J., Resnick, M.A., Bloom, K. (2004) Chromosome Fragmentation after Induction of a Double-Strand Break Is an Active Process Prevented by the RMX Repair Complex Current Biology 14:2107-2112.


Pearson CG, Yeh E, Gardner M, Odde D, Salmon ED, Bloom K (2004) Stable kinetochore-microtubule attachment constrains centromere positioning in metaphase Current Biology 14:1962-1967.

Molk, J., Schuyler, S., Liu, J., Evans, J., Salmon, E.D., Pellman, D., and Bloom, K. (2004) The Differential Roles of Budding Yeast Tem1p, Cdc15p, and Bub2p Protein Dynamics in Mitotic Exit Mol. Biol. Cell 15:1519-1532.

Maddox, P.S., Stemple, J., Satterwhite, L., Salmon, E.D., and Bloom, K. (2003) The minus-end directed motor, Kar3, is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast. Current Biology 19:1423-1428.

Pearson, C.G., Maddox, P.S., Zarzar, T., Salmon, E.D., and Bloom, K. (2003) Yeast kinetochores do not stabilize Stu2 dependent spindle microtubule dynamics. Mol. Biol. Cell 14:4181-4195

Tennessee J. Yoder, Chad G. Pearson, Kerry Bloom, and Trisha N. Davis (2003) The Saccharomyces cerevisiae spindle pole body is a dynamic structure. Mol. Biol. Cell 14: 3494-3505

Salmon, E.D., Shaw, S.L., Waters, J., Waterman-Storer, C.M., Maddox, P.S., Yeh, E., and Bloom, K. (2003) A High Resolution Multimode Digital Microscope System. Methods in Cell Biology 56:185-215

Brian L.Sprague, Chad G.Pearson, Paul S.Maddox, Kerry S.Bloom, E.D.Salmon, and David.J.Odde (2003) Mechanisms of Microtubule-Based Kinetochore Positioning in the Yeast Metaphase Spindle Biophysical Journal  84: 3529 –3546

Mythreye, K., and Bloom, K.S. (2003) Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J. Cell Biol 160: 833-843

Thrower, Douglas, A., Stemple, J., Yeh, E. and Bloom, K. (2003) Nuclear oscillations and nuclear filament formation accompany single-strand annealing repair of a dicentric chromosome in Saccharomyces cerevisiae.  Journal of Cell Science 116: 561-569

Segal, M., Bloom, K., and Reed S.I. (2002) Kar9p-independent microtubule capture at Bud6p cortical sites primes spindle polarity prior to bud emergence in S. cerevisiae. Mol. Biol. Cell. 13: 4141-4155

Gupta, M.L. Jr., Bode, C.J., Pearson, C.G., Thrower, D.A., Suprenant, K.A., Bloom, K.S., and Himes R.H. (2002) Tubulin C354 mutations that decrease microtubule dynamics do not prevent nuclear migration. Mol. Biol. Cell. 13:2919-32

Jacalyn Vogel, Ben Drapkin, JaminaOomen, Dale Beach, Kerry Bloom, and Michael Snyder (2001) Phosphorylation of [gamma]-Tubulin Regulates Microtubule Organization in Budding Yeast. Dev. Cell 1(5):621-631.

Karena A. Kosco, Chad G. Pearson, Paul S. Maddox, Peijing Jeremy Wang, Ian R. Adams, E. D. Salmon, Kerry Bloom, and Tim C. Huffaker (2001) Control of Microtubule Dynamics by Stu2p Is Essential for Spindle Orientation and Metaphase Chromosome Alignment in Yeast Mol. Biol. Cell.12: 2870-2880.

Dale L. Beach and Kerry Bloom. (2001) ASH1 mRNA Localization in Three Acts Mol. Biol. Cell. 12: 2567-2577. Related Movies

Pearson, C., Maddox, P., Salmon, E.D. and Bloom. K. (2001) Budding yeast chromosome structure and dynamics during mitosis. J. Cell Biology 152: 1255-1266. 
Movies: Figure 2, Figure 3, Figure 4a, Figure 4c, Figure 4e

Douglas A. Thrower and Kerry Bloom (2001) Dicentric Chromosome Stretching during Anaphase Reveals Roles of Sir2/Ku in Chromatin Compaction in Budding Yeast. Mol. Biol. Cell. 12: 2800-2812. Related Movies

Maddox, P.S., Bloom, K.S. and E.D. Salmon (2000) The polarity and dynamics of microtubule assembly in the budding yeast Saccharomyces cerevisiae. Nature Cell Biology 2:36-41. 

Segal, M., Maddox, P.S., Salmon, E.D., Bloom, K.S. and Reed, S.I. (2000) Establishment of spindle polarity requires Clb5-dependent kinase in budding yeast. J. Cell Biol. 148:441-451. 

Elaine Yeh, Charlie Yang, Elaine Chin, Paul Maddox, E. D. Salmon, Daniel J. Lew, and Kerry Bloom. (2000) Dynamic Positioning of Mitotic Spindles in Yeast:. Role of Microtubule Motors and Cortical Determinants Mol. Biol. Cell 11: 3949-3961. Figure 5, Figure 7

Marisa Segal, Kerry Bloom, Steven Reed. (2000) Bud6 Directs Sequential Microtubule Interactions with the Bud Tip and Bud Neck during Spindle Morphogenesis in Saccharomyces cerevisiae. Mol. Biol. Cell 11: 3689-3702. 

Beach, D.L., Thibodeaux, J., Maddox, P., Yeh, E., Bloom. K. (2000) The role of the proteins Kar9 and Myo2 in orienting the mitotic spindle of budding yeast. Current Biology 10(23):1497-1506.

Maddox, P., Chin, E., Mallavarapu, A., Yeh, E., Salmon, E.D., Bloom, K. (1999) Microtubule dynamics from mating through the first zygotic division in the budding yeast Saccharomyces cerevisiae. J. Cell Biol. 144:977-987. 

Beach, D.L., Salmon, E.D., and Bloom, K. (1999) Localization and anchoring of mRNA in budding yeast Current Biology 9:569-578. 

Maddox, P. 1999. Researchers Find that mRNA is Actually Green.-not affiliated with THE ONION. 

Theesfeld, C., Irazoqui, J.E., Bloom, K., and Lew, D.J. (1999). The role of actin in spindle orientation changes during the S. cerevisiae cell cycle. J. Cell Biol. 146:1019-1032.

Shaw, S.L., Maddox, P., Skibbens, R.V., Yeh, E., Salmon, E.D. and Bloom, K. (1998) Nuclear and spindle dynamics in budding yeast. Mol. Biol. Cell 9:1627-1631.

Yang, S., Yeh, E., Salmon, E.D. and Bloom K.S. Identification of a Mid-Anaphase Checkpoint in Yeast. (1997). J. Cell Biol. 136:345-354. 

Shaw, S.L., Yeh, E., Bloom, K., and Salmon, E.D. (1997). Imaging green fluorescent protein fusion proteins in Saccharomyces cerevisiae. Current Biology 7:701-704.

Shaw, S.L., Yeh, E., Maddox, P., Salmon, E.D. and Bloom, K. (1997) Astral microtubule dynamics in yeast: A microtubule-based searching mechanism for spindle orientation and nuclear migration in the bud. J. Cell Biol. 139:985-994.

Yeh, E., Skibbens, R., Cheng, J., Salmon, E.D., and Bloom, K. (1995) Spindle dynamics and cell cycle regulation of cytoplasmicdynein in the yeast, S. cerevisiae . J. Cell Biol. 130:687-700.

Brock J. and Bloom, K. (1994) A chromosome breakage assay to monitor mitotic forces in budding yeast. J. Cell Science 107: 891-902. 

Kramer, K.M., Brock, J.A., Bloom, K.S., Moore, J.K., and Haber, J.E. (1994). Two different types of double strand breaks in S. cerevisiae are repaired by similar RAD52 non-homologous recombination events. Mol. Cell Biol. 14:1293-1301.

Schulman, I. and Bloom, K. S. (1993). Genetic Dissection of Centromere Assembly. Mol.Cell Biol.13: 3156-66. 

Heus, J.J., Zonneveld, B.J.M., Bloom, K.S., Steensma, H.Y. and van den Berg, J.A. (1993). The nucleosome repeat length of K. lactis is 16 bp longer than that of S. cerevisiae. NAR 21:2247-2248. 

Li, Y.-Y., Yeh, E., Hays, T., and Bloom, K. (1993). Disruption of Mitotic spindle orientation in a Yeast Dynein mutant. Proc. Natl. Acad. Sci. USA 90:10096-10100.

Resnick, M.A., Westmoreland, J., and Bloom, K. (1990). Heterogeneity and maintenance of centromere plasmid copy number in S. cerevisiae. Chromosoma 99:281-288. 

Saunders, M.A., Grunstein, M. and Bloom, K.S. (1990). Nucleosome Depletion Alters the Chromatin Structure of a Yeast Centromere. Molec Cell. Biology 10: 5721-5727. 

Yeh, E., Driscoll, R., Coltrera, M., Olins, A. and Bloom, K. (1990). A dynamin like protein encoded by the yeast sporulation gene SPO15. Nature 349: 713-715.

Hill, A., and Bloom, K.S. (1989) The Acquisition and Processing of Dicentric Chromosomes in Yeast. Molecular and Cellular Biology 9:1368- 1370.

Saunders, M.A., Fitzgerald-Hayes, M. and Bloom, K.S. (1988). Chromatin Structure of Altered Yeast Centromeres. Proc. Natl. Acad. Sci. USA 85:175-179. 

Kenna, M., Amaya, E. and Bloom K.S. (1988). Selective Excision of the Centromere Chromatin Complex from Saccharomyces cerevisiae. J. Cell Biol. 107:9-15.

Hill, A., and Bloom, K. (1987). Genetic Manipulation of Centromere Function Molecular and Cellular Biology 7:2397-2405.

Yeh, E., Carbon, J. and Bloom, K. (1986). Tightly centromere-linked gene (SPO15) essential for meiosis in the yeast Saccharomyces cerevisiae. Molecular and Cell Biology. 6: 158-167.

Bloom, K.S., Amaya, E., Carbon, J., Clarke, L., Hill, A, and Yeh, E. 1984. Chromatin Conformation of Yeast Centromeres. J. Cell Biology. 99: 1559-1568.

Bloom, K.S. and Carbon, J. 1982. Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular mini-chromosomes. Cell 29: 305-317.
 


Monographs and Invited Reviews (total of 27):

Bloom, K. Beyond the code: the mechanical properties of DNA as they relate to mitosis  Chromosoma

Joglekar, A., Salmon, E.D., and Bloom, K.(2007) Counting Kinetochore Protein Numbers in Budding Yeast Using Genetically Encoded Fluorescent Proteins Methods in Cell Biology 85:127-151.

Maher, B. (2007) Spring Theory Nature 448:984-986.

Bloom, K. (2006) NoCut: Cytokinesis in Check  Cell  125:17-18.

Bloom, K. (2005) Chromosome Segregation: Seeing Is Believing Current Biology 15:R500-R503.

Bouck, D. and Bloom, K. (2005) The role of centromere-binding factor 3 (CBF3) in spindle stability, cytokinesis, and kinetochore attachment  Biochem Cell Biology 83:696-702.

Bloom, K. (2004) Microtubule composition: Cryptography of dynamic polymers Proceedings of the National Academy of Sciences USA 101:6839-6840.

Pearson, C. G. and Bloom, K. (2004) Dynamic microtubules lead the way for spindle positioning Nature Reviews Cell and Molecular Biology 5:481-492.

Bloom, K. (2003) Microtubule Cytoskeleton: Navigating the Intracellular Landscape Current Biology, 13: R430–R432

Bloom, K., (2002)Yeast weighs in on the elusive spindle matrix: Proc. Natl. Acad. Sci. USA 99:4757-4759.

Segal, M., and Bloom, K. (2001) Control of Spindle Polarity and Orientation in Saccharomycescerevisiae. Trends in Cell Biology 11:160-166 

Bloom, K. (2001) Nuclear Migration: Cortical anchors for cytoplasmicdynein. Current Biology 11:326-329

Bloom, K. (2000) It's a kar9ochore to capture microtubules. Nature Cell Biology 2:96-98.

Bloom, K. and Beach, D.L. (1999). mRNA localization: Motile mRNA, asymmetric anchors. Current Opinion in Microbiology: Genetics and Development 2:604-609.

Salmon, E.D., Shaw, S.L.,Waters, J., Waterman-Storer, C., Maddox, P.S., Yeh, E., and Bloom, K. (1998) A High-Resolution Multimode Digital Microscope System. Methods in Cell Biology 56:186-216. 

Bloom, K., Beach, D.L, Maddox, P., Shaw, S.L., Yeh, E., and Salmon, E.D. (1998). Using GFP Fusion Proteins to Quantitate Microtubule and Spindle Dynamics in Budding Yeast. Methods in Cell Biology 61:369-383.

Bloom, K. (1993). The Centromere Frontier: Kinetochore components, microtubule-based motility and the Cen-value paradox.Cell 73: 621-624. 

Schulman, I. and Bloom, K. (1991). Centromeres: An Integrated Protein/DNA Complex required for chromosome movement. Annual Review in Cell Biology Vol. 7:311-336.



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