CURRICULUM VITAE (long version)
Alan Monte Jones
Department of Biology
(919) 962-6932 fax 962-1625
email: alan_jones@unc.edu
EDUCATION
Ph.D. Plant Biology, 1983,
B.S. cum laude, Botany, 1978,
EMPLOYMENT
1999-present Professor of Biology, University of North
Carolina-Chapel Hill
1992-1999, Associate
Professor of Biology, Univ. of North Carolina-Chapel Hill
1986-1992 Assistant Professor
of Biology, Univ. of North Carolina-Chapel Hill
1983-1986 Res. Associate for
Dr. Peter Quail, Botany,
1982-1983 Research Assistant
for Dr. David Ho, Univ. of
1981-1982 Research Assist.
for Dr. Fred Meins, Friedrich Miescher Inst. in
1978-1981 Res Assist. for
Dr. Larry Vanderhoef, Plant Biology,
PROFESSIONAL
2002- Regular panel member,
NSF, Cell Biology Signal Transduction
2002- Regular study section
member, NIH, SSS-Y
2001 USDA NRICGO, Panel Manager
1999 Panel member, NIH Molecular Biology, CDF-1
1991-1998 Editor, Plant
Physiology
1998- Faculty member in
Program in Genetics and Molecular Biology
1997- Faculty member in
Program in Cell Biology
1991-1996, Faculty member in
the Program for Protein Engineering and Molecular Biology
1999- Editorial Board, J. Plant Growth Regulation
1992-1996 Associate Editor, J. Plant Growth Regulation
Member: AAAS, IPGSA, ISPMB,
ASCB, ASPP, NCAS
1991-1993 USDA NRICGO, panel
member
BARD Program CoChairman,
1995; BARD Chairman 1996
HONORS AND AWARDS
1996 Alexander von Humboldt
Research Fellow
1987 John T. Lupton Award
for Teaching Improvements
1987 IBM Junior Faculty
Award
1982
PUBLICATIONS
Hayashi, K., Jones, A.M., Ogino, K.,
Yamazoe, A., Oono, Y., Inoguchi, M., Kondo, H. and Nozaki, H. (2003) Yokonolide B, a novel inhibitor of auxin
action, blocks degradation of Aux/IAA factors. J. Biol. Chem. (in press)
Jones, AM, Ecker, JR, Chen J-G (2003) A
Re-evaluation of the Role of the Heterotrimeric G Protein in Coupling Light
Responses in Arabidopsis. Plant Physiol. in press
Ullah, H., Chen, J-G.,
Temple, B., Boyes, D.C., Alonso, J.M., Davis, K.R., Ecker, J.R., Jones, A.M. (2003)
The Beta Subunit of the Arabidopsis G Protein Negatively Regulates
Auxin-induced Cell Division and Affects Multiple Developmental Processes. Plant Cell 15: 393-409
Groover, A., Chen, J-G.,
Pattishall, A., and Jones, A.M. (2003) Auxin regulation of Arabidopsis
IAA8 and zinnia zIAA8 in vascular development. Plant Mol. Biol. (in press) featured on the cover
Höglund, A-S., Jones, A.M., and Josefsson, L-G. (2002)
An Antigen Expressed During Plant Vascular Development Cross-Reacts With
Antibodies Towards KLH, keyhole limpet hemocyanin J. Histochem. 50:999-1003
Yu, X., Perdue, A, Heimer,
Y., Jones, A. (2002) Mitochondrial
participation in tracheary element cell death.
Cell Death and Differentiation 9: 189-198
Chen, J-G., Shimomura, S., Sitbon, F., Sandberg, G., Jones, A.M. (2001) Role of auxin-binding protein 1 in leaf cell growth. Plant J. 28:607-617.
Wang, X-Q., Ullah, H., Jones, A.M., Assmann, SM
(2001) G-protein regulation of ion channels and abscisic acid signaling in Arabidopsis guard cells Science
292: 2070-2072
Ullah, H. Chen, J. G.,
Young, J., Im, K-H., Sussman, MR., Jones, AM (2001) Modulation of Cell Proliferation by Heterotrimeric
G-protein in Arabidopsis. Science 292: 2066-2069
Fischer-Iglesias,
C, Sundberg, B, Neuhaus, G and Jones, A.M.
(2001) Auxin distribution and transport during embryonic pattern
formation in wheat Plant J. 26:
115-129.
Chen, J, Ullah, H., Young, J.C., Sussman, M.R., Jones, A.M (2001) ABP1 is required for organized
cell elongation and division in Arabidopsis embryogenesis. Genes and
Development 15:902-911. featured
on the cover
Im,
K., Chen, J-G., Meeley, R., Jones, A.M (2001) Auxin-binding protein mutants in
maize.
Maydica 45:
319-325
Im,
H, Cosgrove, D, Jones, AM (2000) Subcellular localization of expansin mRNA in
xylem cells. Plant Physiol.123:
463-470. featured on the cover
DeWitt, G., Richards, J., Mohnen, D and Jones,
A.M. (1999) Comparative compositional analysis
of walls with two
different morphologies: archetypical versus transfer-cell like.
Protoplasma
209: 238-245
Groover,
A., Jones, A.M. (1999) Tracheary
Element Differentiation Uses a Novel Mechanism Coordinating Programmed Cell
Death and Secondary Cell Wall Synthesis. Plant Physiology 119:375-384.
featured on the cover
Shillito, and Andrew Binns. (1998) Auxin-dependent cell expansion
mediated by overexpressed auxin-binding protein 1. Science 282: 1114-1117
Brown,
Justin C., Parachuri Prasad, Ming-Jing Wu, Gerard P. Irzyk and Alan M. Jones
(1998) Purification of a
65-kilodalton Nuclear Protein with Structural Homology to Glutathione- S-transferase. Plant Science 136:
227-236.
Shinkle,
J. R., Kadakia, R., Jones. A. M. (1998) Dim-red-light induced increase in polar
auxin transport in cucumber seedlings: I.
Development of altered capacity, velocity, and
response to inhibitors. Plant Physiol. 116:
1505-1513
Barker-Bridgers,
M., Ribnicky, D.M., Cohen, J.D. Jones, A.M. (1998) Red-light regulated growth. II. Changes in the abundance of
indoleacetic acid in the maize mesocotyl. Planta 204: 207-211
Groover, A.T., DeWitt, N.G.,
Heidel, A.J., Jones, A.M. (1997) Programmed cell death of plant tracheary
elements differentiating in vitro. Protoplasma 196: 197-211.
Tian, H., Klambt, D. and
Jones, A.M. (1995) Auxin-binding protein 1 does not bind auxin within the endoplasmic reticulum despite
this being the predominant subcellular location for this hormone receptor. J. Biol. Chem. 270:26962-26969
Harnden, D. and Jones, A.M.
(1995) Organ localization of auxin-binding protein 1 in the etiolated maize seedling. J.
Plant Growth Reg. 14:109-113
Brown, J. C. and Jones, A.
M. (1994) Mapping the auxin-binding site of auxin-binding protein 1. J.
Biol. Chem. 269: 21136-21140
Edgerton, M.D. Tropsha, A.
and Jones, A.M. (1994) The auxin-binding site of auxin-binding protein 1.
Phytochemistry 35:1111-1123
Edgerton, M.D. and Jones, A.M. (1993) Subunit
interactions in the carboxy-terminal domain of
phytochrome. Biochemistry 32:8239-8245
Edgerton, M.D.,
Jones, A. M. and Herman, E.
(1993) KDEL-containing, auxin-binding protein is secreted to the plasma
membrane and cell wall. Plant Physiol. 101:595-606
Frances, S., White, M.J.,
Edgerton, M. D., Jones, A.M., Elliot, R.C., and Thompson, W.F. (1992) Initial characterization of a pea
mutant with light-independent photomorphogenesis.
Plant Cell 4: 1519-1530
Jones, A.M, D.S. Cochran,
P.L. Lamerson, J. Cohen, M. Evans (1991) Red- light induced changes in auxin, an auxin-binding
protein, and auxin transport in maize mesocotyl. Plant Physiol. 97:352-358
Prasad, P.V., A.M. Jones
(1991) A putative receptor for the plant growth hormone, auxin identified and charactertized by anti-
idiotypic antibodies. Proc. Natl. Acad.
Sci. USA 88:5479-5483.
Macdonald, H., A.M. Jones,
P.J. King (1991) Photoaffinity labeling of soluble auxin-binding proteins. J. Biol. Chem. 266:7393-7399
Zhou, S., A.M. Jones, T.K.
Scott (1990) Phytochrome-mediated Swelling of Etiolated Leaf Protoplasts and Its Possible In vivo
Significance. Plant Cell Reports 9:435-438
Jones, A.M., P. Lamerson,
M.A. Venis (1989) Comparison of Site I Auxin Binding and a 22- Kilodalton Auxin-binding Protein in Maize. Planta 179:409-414
Jones, A.M. (1990) Location
of Transported Auxin in Etiolated Maize Shoots Using 5- azidoindoleacetic acid. Plant
Physiol. 93:1154-1161
Jones, A.M., M.A. Venis
(1989) Photoaffinity Labeling of Auxin-Binding Proteins in Maize. Proc.
Natl. Acad. Sci. USA 86:6153-6156
Hicks, G. R., Rayle, D. L.,
Jones, A. M., Lomax, T. L. (1989) Specific Photoaffinity Labeling of Two Plasma Membrane Polypeptides
with an Azido Auxin. Proc. Natl. Acad. Sci. USA 86:4948-4952
Jones, A.M., P.H. Quail
(1989) Phytochrome Structure: Peptide fragments from the amino- terminal domain involved in protein-
chromophore interactions. Planta 178:147-156
Jones, A.M., H.P.
Erickson (1989) Domain Structure of
Phytochrome from Avena
sativa Visualized by Electron Microscopy. Photochem. Photobiol. 49:479-483
Parks, B.M., A.M. Jones, P.
Adamse, M. Koorneef, R.E. Kendrick, and P.H. Quail (1987) The Aurea Mutant of Tomato is Deficient in
Spectrometrically and Immunochemically Detectable
Phytochrome. Plant Mol. Biol. 9:97-108.
Jones, A.M., C.D. Allen, G. Gardner, and P.H. Quail (1986) Synthesis of
Phytochrome Apoprotein and
Chromophore are not Coupled Obligatorily. Plant
Physiol. 81:1014-1016.
Jones, A.M. and P.H.Quail
(1986) Quaternary Structure of 124-Kilodalton Phytochrome from Avena
sativa L. Biochemistry 25:2987- 2995.
Jones, A.M., R.D. Vierstra,
S.M. Daniels, and P.H. Quail (1985) The Role of Separate Molecular Domains in the Structure of
Phytochrome from Etiolated Avena sativa L.
Planta 164:501-506.
Jones, A.M., L.L. Melhado, T.-H.D.
Ho, C.J. Pearce, and N.J. Leonard (1984) Azido Auxins: Photoaffinity Labeling of Auxin-Binding Proteins in Maize
Coleoptile with Tritiated 5- azidoindole-3- acetic acid. Plant Physiol 75:1111-1116.
Melhado, L.L., A.M. Jones,
T.-H.D. Ho, and N.J. Leonard (1984) Azido Auxins: Photolysis in Solution
and Covalent Binding to Soybean. Plant
Physiol 74:289-294.
Jones, A.M., l.l. Melhado,
T.-H.D. Ho, and N.J. Leonard (1984) Azido Auxins: Quantitative Binding Data in Maize. Plant Physiol. 74:294-302.
Melhado, LL, Jones, AM,
Jones, A.M. and L.N.
Vanderhoef (1980) The Effect of Abrading the Cuticle. J.
Expt. Bot. 32:405-410.
Book Chapters and Invited
Reviews:
Jones, AM (2002)
G-protein-coupled signaling in Arabidopsis. Curr.
Opin. Plant Biol. 5:402-407
Jones, A. M. ed. 2001 Special
Edition on Auxins. J. Plant Growth Reg. Vol. 20 number 3
Jones, A. M., A. Groover, X
Yu, T. Perdue (2001) Final and fatal step of tracheary element differentiation.
In Molecular Breeding of Woody Plants, N. Morohoshi and A. Komamine,
eds. Elsevier Science B. V. pp. 29-42
Jones, A M (2001) Programmed
cell death in development and defense. Plant Physiol. 125: 94-97
Jones, A.M. (2000) Does the plant mitochondrion integrate
cellular stress and regulate programmed cell death? Trends
in Plant Sciences 5, 225-230
Jones, A.M. (1999)
Manipulation of fiber content in plants.
AgriNews 1: 1-4
Jones, A.M. (1999) Textbook review ‘Introduction to Plant
Physiology, 2nd edtion by William C.
Jones, A.M. (1998) Auxin
transport: Down and out and up again. Science
282: 2201-2202
Jones, A.M. and Dangl, J. D.
(1996) Logjam at the
Jones, A.M. and Lomax, T. L.
(1996) Photoaffinity labeling with
5-azidoindole-3-acetic acid. In Plant
Biochemistry and Molecular Biology, CRC Press, pp. 115-132
Jones, A.M. and Edgerton, M.
D. (1994) The Anatomy of phytochrome: a unique photoreceptor in plants. Seminars in Cell Biology 5:295-302
Jones, A. M. (1994)
Surprising signals in plants. Science
263:183-184
Jones, A. M. (1994)
Auxin-binding proteins. Annu. Rev. Plant
Physiology and Plant Molecular
Biology 45:393-420
Jones, A. M. (1993)
Auxin-binding proteins and their possible role in cell development. Cellular
Communication in Plants.
Amasino, R., ed., Plenum, NY
Jones, A.M. (1992) What
remains of the Cholodney-Went theory? Assymetric redistribution of auxin need only occur over the distance
of one cell width. Plant Cell Environ. 15: 775-776.
featured on the cover
Jones, A.M., P.V. Prasad
(1991) Auxin-binding proteins and their possible roles in auxin- mediated plant growth. BioEssays 14:43-48
Jones, A.M. 1990 Do We Have
the Auxin Receptor Yet? Physiol. Plant.
80:154-158
Quail, P.H., Christensen,
A.C., Jones, A.M., Lissemore, J.L., Parks, B.M., Sharrock, R.A. (1987) The Phytochrome Molecule and the
Regulation of its Genes. In 4th
FOAB Congress, Integration and
Control of Metabolic Processes: Pure and Applied Aspects, ICSU Press. pp 41-54
Jones, AM Venis, MA (1987)
Photoaffinity Labeling of auxin-binding proteins in maize. In "Physiology and Biochemistry of
Auxins in Plants" Kutacek, Bandurski, Krekule, eds.
Jones, AM (1987) The effect
of low fluence red light on growth and NAA binding. In "Physiology and Biochemistry of Auxins in Plants"
Kutacek, Bandurski, Krekule, eds.
Quail, P.H., Barker, R.F.,
Colbert, J.T., Daniels, S.M., Hershey, H.P., Idler, K.B., Jones, A.M., and
Lissemore, J.T. (1986) In Molecular Biology of Plant Growth Control,
UCLA Symposium on Molecular and Cellular
Biology, Alan R. Liss, Inc., pp 425-439
Quail, P.H., Gatz, C., Hershey, H.P., Jones, A.M.,
Lissemore, J.L., Parks, B.M., Sharrock,
R.A., Barker,, R.F., Idler,, K.,
Trewavas, A.J. and A.M.
Jones (1981) Consequences of hormone binding studies for plant growth research. What's New in Plant
Physiology? 12:5-8.
Starling, R.J., A.M. Jones,
and A.J. Trewavas (1985) Putative Plant Hormone Receptors. What's New
in Plant Physiology? 15:37-40
Jones, A.M., A.S.N. Reddy,
1992 Auxin. McGraw-Hill Yearbook of Science and Technology
[PDES1]INVENTION DISCLOSURES AND PATENTS (UNC-CH
only)
ORS94-78 In vivo expression system for detection
of homotypic protein-protein interactions
OTD96-91 A controllable genetic mechanism to
increase the growth rate of plants
OTD98-25
A genetic mechanism to increase the growth rate of plants
OTD00-101 Plant cell expansion control by ABP1.
(Patent Pending)
OTD02- Hyperpolarization-activated Ca++
channels as reporters for membrane hyperpolarization
Docket # 2155P
Methods of improving plant agronomic traits by altering the expression
of plant G proteins alpha and beta. (Patent Pending)
MAJOR PRESENTATIONS (1986-present)
“University-Industry
Relationships and the public good, the bad, and the ugly”, Agricultural Biotechnology Worshop held Nov.
19-20,
“Role of the
beta subunit of Arabidopsis Heterotrimeric G Protein in Controlling Cell
Division” Dept. Biology, Penn State
Univ. Oct. 15th, 2002
“Role of the
Mitochondria in Programmed Cell Death During Tracheary Element Differentiation”
Am. Phytopathological Society, Symposium Speaker,
"Life in the Fastlane- a Perspective from a Principal
Investigator" Burroughs Welcome Fund sponsored Conference on Electronic
Grantmaking.
"Multiple
Signal Coupling by Arabidopsis Heterotrimeric G protein”
"Multiple Signal Coupling by
Arabidopsis Heterotrimeric G protein"
Max Plank Institute,
“Dual and competing auxin signal
transductions by independent pathways” , 2nd Internat’l Conference DFG
Schwerpunktprogramm Molecular Analysis of Phytohormone Action.
"Dual auxin
signal mechanisms involves G protein coupling in Arabidopsis", Cell
and Molecular Biology, Univ. Texas- Austin,
"Role
of a heterotrimeric G-protein in signal crosstalk in seed germination" Plenary speaker for
“ABP1 is required for coordinated cell elongation and division in
arabidopsis embryogenesis”, XIV International Congress on Plant Growth
Regulators,
“Auxin control
of plant cell growth and division” Dept.
Chemisty, UNC-CH,
“Signal
transduction of plant cell division and expansion”, 4 talks given in
“Final and Fatal Step of Tracheary Element
Differentiation” International Symposium on Tree Biotechnology,
“Signal
transduction pathways in plant cell elongation, division and differentiation”,
Cold Spring Harbor Lab, Banbury Conference,
“Regulation
of programmed cell death during tracheary element formation by a novel
‘trigger’ protease” Univ.
“A novel
protease controlling programmed cell death during tracheary element
differentiation”, NCBC annual PMB retreat, Boone, NC invited speaker, Set. 16,
2000
“Regulation of Programmed Cell Death During
Tracheary Element Differentiation”, Invited speaker and session chair,
Gordon Conference,
“'Mediation of auxin action through the auxin
receptor”, Plenary, ABP1' Plant Growth
Regulator Society of America, Kona
“Auxin signal
transduction” Auxin 2000,
“Programmed Cell
Death in Plants” Cell Death Society
Symp,
“New targets for
auxenic herbicides” DowAgro,
“ Induction and
termination: two controlling events of tracheary element formation”, Dept.
Forestry, Univesity of Sweden,
“Dual signalling
pathways for auxin-regulated cell division and expansion” Dept. of Forestry,
“Regulation of programmed cell death by a secreted
protease during terminal differentiation of tracheary elements”
American Soc. Cell Biology,
“How to become a
functional corpse: Lessons from a model cell system” Dept. Biology, The University of North
Carolina at
“Regulation of programmed cell death by a secreted
protease during terminal differentiation of tracheary elements.”,
“Programmed cell
death during differential differentiation of tracheary elements” Invited speaker to International Botanical
Congress,
“A two-decade
journey towards an auxin receptor”