Mail to Instructor: Sarah Grant
Compiled data from Tuesday's FASTPLANTS lab class Aug 26
Compiled data from Wednesday's FASTPLANTS lab class Aug 27
average was 32/40
average was 31/40
Answer Key: Final Exam
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Aug. 25 Genes, Alleles and Epistasis
For review: Genes, and alleles, complementation : Hartl and Jones Chapter 3 pp. 90-112, Chi-square test pp. 162-165.
Aug 26/27 Lab 1: Mendelian Genetics using Fast Plants
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Please also look at the FastPlants web site: http://www.fastplants.org
Report due Sept. 9/10.
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Sept. 1 Labor Day - No lecture but labs will be held this week.
Sept. 2/3 Lab 2: Pipetteman and and Titration Exercise, Genes and Alleles in yeast.
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Readings from Manny, T., Davis, L., Johnson, B., Manney, M., Montelone, B., Weaver, L., and Williamson, B. 1997. A Classroom Guide to Yeast Experiments Kansas State University. Distributed by Carolina Biologicals.
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Reading - A Closer Look at Adenine-requiring Mutants in Yeast--
Report due Sept. 16/17.
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Sept. 8 Mouse Models and Epistasis.
For Review: Hartl and Jones pp. 112-125.
Sept. 11/12 Epistasis using mice
Report due Sept. 23/24.
Report on Mendelian Genetics Using Fast Plants due in lab this week.
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Sept. 15 Mutagenesis.
For Review: Hartl and Jones pp. 592-604, 612-636..
Reading - A Closer Look at Biological Consequences of UV exposure
Optional Reading Mouse mutagenesis: Du 2004
Optional Reading Mouse mutagenesis: Beutler 2005
Sept. 16/17 Mutation in Yeast.
Report due Sept. 30/Oct. 1.
Report on Genes and Alleles in yeast due in lab this week.
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Sept. 22 Bacterial Genetics.
Reading to read before class and discuss in class: Lederberg and Tatum 1946.
For Review: Hartl and Jones pp. 344-369.
For interest: E. coli genome comparisons Brzuszkiewicz et al 2006
Pseudomonas syringae genome comparisons Chang et al 2005
Sept. 23/24 Bacterial Genetics.
Report due Oct. 7/8.
Report on Genes Alleles and Epistasis Lab due in lab this week.
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Sept. 29 C. elegans as a model system and epigenetics.
For Review: Hartl and Jones pp. 558-562.
Sept. 30/Oct. 1 and Oct. 7/8 C. elegans genetics and RNAi.
Report due: Oct. 21/22
Report on Mutation Lab due in lab this week.
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Oct. 6 Midterm1 in class. Will cover up to Bacterial Genetics Lab and associated lecture material.
Oct. 7/8 C. elegans genetics and RNAi will continue.
Report due: Oct 21/22.
Report on Bacterial Genetics Lab due in lab this week.
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Oct. 13 Introduction to Mapping
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Readings for class: Hartl and Jones pp. 105-112, 176-203, 194-198 565-580.
Research Paper topics due in writing in class
Oct. 14/15 to Nov11/12 Drosophila Genetics.
Report on Drosophila lab due Nov. 25. ____________________________________________________________________
Oct. 20 DNA cloning.
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For review: Hartl and Jones pp. 53-62, 502-518.
Oct. 21/22 Cloning Lab.
Report due: Nov 4/5.
Report on C. elegans lab due in lab this week.
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Oct. 27 Map based cloning of the Huntington Disease gene
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Readings for class:
Outlines for research papers due in lecture period.
Oct. 28/29 Drosophila lab continues, test cross, score for sex-linked traits.
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Nov. 3 Association mapping for Human diseases Guest Lecturer: Karen Mohlke
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Reading: Hartl and Jones Chapter 18
Nov. 4/5 Association mapping lab
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Bring your laptop to the lab class
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We will email the data files to you in case you cannot
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download them from the sites below.
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Be sure to have them available on your computer for lab class.
Report due Nov. 18/19.
Report on Cloning Lab due in lab this week.
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Nov. 10 Midterm in class. Will cover up to Drosophila as a model system. Will not cover three-point cross.
Nov. 11/12 Drosophila lab continues, score results of test cross.
Report due Nov. 25/26. Write a standard lab report with abstract, introduction results and discussion.
No reports due this week. Work on your research paper!!!
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Nov. 17 DNA markers and Forensics. Read the first two papers posted on this page, below, before class and be ready to discuss in class.
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Hartl and Jones pp. 62-79, 731-734.
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Reading - Lander and Ellis News and Views 1998.
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Reading - Foster et. al. 1998 Jefferson data
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Suggested Reading - Sobrino et al. 2005 SNP analysis methods
Nov 18/19 Forensics lab: Human DNA, PCR and variation
Report Due Dec 2/3. Write a standard lab report with abstract, introduction results and discussion.
Report on Association mapping lab due this week. (short format)
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Nov. 24 Map-based cloning in model organisms.
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Physical Mapping of genes: Hartl and Jones pp. 514-515, 518-521.
There will be no lab class this week because of Thanksgiving.
Research papers due in class Monday Nov. 24.
Report on Drosophila lab due this week.
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Dec. 1 Review.
Dec. 2/3 Map-Based Cloning Lab. Bring your computers to the lab class again.
There will be no lab report but there will be questions on this exercise on the final exam.
Report on Forensics lab due this week.
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Dec. 8 Final Exam in 106 Gardner Hall 12:00 noon - 3:00 pm. Covers entire course.
